2,4-Dichloro-3-methoxyquinoline

Base Information

• Chemical Name: 2,4-Dichloro-3-methoxyquinoline
• CAS No.: 157027-29-7
• Molecular Formula: C₁₀H₇Cl₂NO
• Molecular Weight: 228.078
• DSSTox Substance ID: DTXSID60379542
• Wikidata: Q82169400
• Mol file: 157027-29-7.mol

Synonyms:2,4-dichloro-3-methoxyquinoline;157027-29-7;DTXSID60379542;FT-0733251

Chemical Property of 2,4-Dichloro-3-methoxyquinoline

Chemical Property:

• Vapor Pressure: 0.000508mmHg at 25°C
• Boiling Point: 323°Cat760mmHg
• Flash Point: 149.2°C
• PSA: 22.12000
• Density: 1.384g/cm³
• LogP: 3.55020
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 226.9904692
• Heavy Atom Count: 14
• Complexity: 203

Purity/Quality:

97% ^*data from raw suppliers

2,4-DICHLORO-3-METHOXYQUINOLINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C2=CC=CC=C2N=C1Cl)Cl

Technology Process of 2,4-Dichloro-3-methoxyquinoline

There total 1 articles about 2,4-Dichloro-3-methoxyquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-hydroxy-3-methoxy-2(1H)-quinolinone (15151-56-1) → 2,4-Dichloro-3-methoxy-quinoline (157027-29-7)

Guidance literature:

With trichlorophosphate; for 0.5h; Heating;

DOI:10.1002/prac.19943360407

upstream raw materials:

4-hydroxy-3-methoxy-2(1H)-quinolinone