methyl 2-methyl-3-phenyl-3-(p-toluenesulfonylamino)propanoate

Base Information

• Chemical Name: methyl 2-methyl-3-phenyl-3-(p-toluenesulfonylamino)propanoate
• CAS No.: 1223579-20-1
• Molecular Formula: C₁₈H₂₁NO₄S
• Molecular Weight: 347.435
• Mol file: 1223579-20-1.mol

Synonyms:methyl 2-methyl-3-phenyl-3-(p-toluenesulfonylamino)propanoate

Chemical Property of methyl 2-methyl-3-phenyl-3-(p-toluenesulfonylamino)propanoate

Chemical Property:

Purity/Quality:

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Technology Process of methyl 2-methyl-3-phenyl-3-(p-toluenesulfonylamino)propanoate

There total 1 articles about methyl 2-methyl-3-phenyl-3-(p-toluenesulfonylamino)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

methyl 2-methyl-3-phenyl-3-(p-toluenesulfonylamino)propanimidate hydrochloride (1223579-06-3) → methyl 2-methyl-3-phenyl-3-(p-toluenesulfonylamino)propanoate (1223579-20-1)

Guidance literature:

With water; at 55 ℃; for 7h;

DOI:10.1021/ol100073y

Reference yield: 63.0%

methyl 2-methyl-3-phenyl-3-(p-toluenesulfonylamino)propanoate (1223579-20-1) → N-(3-hydroxy-2-methyl-1-phenylpropyl)-4-methylbenzenesulfonamide (127598-09-8)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 2.5h;

DOI:10.1021/ol100073y

upstream raw materials:

methyl 2-methyl-3-phenyl-3-(p-toluenesulfonylamino)propanimidate hydrochloride

Downstream raw materials:

N-(3-hydroxy-2-methyl-1-phenylpropyl)-4-methylbenzenesulfonamide