4-(4-chlorophenyl)-2-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosylmercapto)-6-(thien-2-yl)nicotinonitrile

Base Information

• Chemical Name: 4-(4-chlorophenyl)-2-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosylmercapto)-6-(thien-2-yl)nicotinonitrile
• CAS No.: 1421755-93-2
• Molecular Formula: C₃₀H₂₇ClN₂O₉S₂
• Molecular Weight: 659.137

Synonyms:4-(4-chlorophenyl)-2-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosylmercapto)-6-(thien-2-yl)nicotinonitrile

Chemical Property of 4-(4-chlorophenyl)-2-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosylmercapto)-6-(thien-2-yl)nicotinonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(4-chlorophenyl)-2-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosylmercapto)-6-(thien-2-yl)nicotinonitrile

There total 2 articles about 4-(4-chlorophenyl)-2-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosylmercapto)-6-(thien-2-yl)nicotinonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

4-(4-chlorophenyl)-6-(thien-2-yl)-2-thioxo-1,2-dihydropyridine-3-carbonitrile (82127-15-9) + 1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside (3068-32-4) → 4-(4-chlorophenyl)-2-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosylmercapto)-6-(thien-2-yl)nicotinonitrile (1421755-93-2)

Guidance literature:

4-(4-chlorophenyl)-6-(thien-2-yl)-2-thioxo-1,2-dihydropyridine-3-carbonitrile; With potassium carbonate; In N,N-dimethyl-formamide; acetone; for 1h;

1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside; In N,N-dimethyl-formamide; acetone; at 20 ℃; regioselective reaction; Reflux;

DOI:10.1007/s11164-012-1006-y

Reference yield:

4-(4-chlorophenyl)-2-oxo-6-(thien-2-yl)-1,2-dihydropyridine-3-carbonitrile (120238-95-1) → 4-(4-chlorophenyl)-2-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosylmercapto)-6-(thien-2-yl)nicotinonitrile (1421755-93-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: tetraphosphorus decasulfide / pyridine / 6 h

2.1: potassium carbonate / N,N-dimethyl-formamide; acetone / 1 h

2.2: 20 °C / Reflux

With tetraphosphorus decasulfide; potassium carbonate; In pyridine; N,N-dimethyl-formamide; acetone;

DOI:10.1007/s11164-012-1006-y

Reference yield: 90.0%

4-(4-chlorophenyl)-2-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosylmercapto)-6-(thien-2-yl)nicotinonitrile (1421755-93-2) → 4-(4-chlorophenyl)-2-(β-D-galatcopyranosylmercapto)-6-(thien-2-yl)nicotinonitrile (1421755-95-4)

Guidance literature:

With water; triethylamine; In methanol; at 20 ℃;

DOI:10.1007/s11164-012-1006-y

upstream raw materials:

4-(4-chlorophenyl)-6-(thien-2-yl)-2-thioxo-1,2-dihydropyridine-3-carbonitrile

1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside

4-(4-chlorophenyl)-2-oxo-6-(thien-2-yl)-1,2-dihydropyridine-3-carbonitrile

Downstream raw materials:

4-(4-chlorophenyl)-2-(β-D-galatcopyranosylmercapto)-6-(thien-2-yl)nicotinonitrile

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1421755-93-2 4-(4-chlorophenyl)-2-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosylmercapto)-6-(thien-2-yl)nicotinonitrile

Send

Send

Metric Ton KG G Pound L ML

Send

Send