4-chloro-2-(4-(trifluoromethyl)benzoyl)phenyl dimethylcarbamate

Base Information

• Chemical Name: 4-chloro-2-(4-(trifluoromethyl)benzoyl)phenyl dimethylcarbamate
• CAS No.: 1452841-71-2
• Molecular Formula: C₁₇H₁₃ClF₃NO₃
• Molecular Weight: 371.743
• Mol file: 1452841-71-2.mol

Synonyms:4-chloro-2-(4-(trifluoromethyl)benzoyl)phenyl dimethylcarbamate

Chemical Property of 4-chloro-2-(4-(trifluoromethyl)benzoyl)phenyl dimethylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 4-chloro-2-(4-(trifluoromethyl)benzoyl)phenyl dimethylcarbamate

There total 2 articles about 4-chloro-2-(4-(trifluoromethyl)benzoyl)phenyl dimethylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

O-(4-chlorophenyl)-N,N-dimethylcarbamate (7305-03-5) + 4-(trifluoromethyl)phenylglyoxylic acid (79478-02-7) → 4-chloro-2-(4-(trifluoromethyl)benzoyl)phenyl dimethylcarbamate (1452841-71-2)

Guidance literature:

With ammonium peroxydisulfate; trifluorormethanesulfonic acid; palladium diacetate; In 1,2-dichloro-ethane; at 20 ℃; for 20h; Sealed tube;

DOI:10.1002/adsc.201200993

Reference yield:

1-(4-trifluoromethylphenyl)ethanone (709-63-7) → 4-chloro-2-(4-(trifluoromethyl)benzoyl)phenyl dimethylcarbamate (1452841-71-2)

Guidance literature:

Multi-step reaction with 2 steps

1: selenium(IV) oxide; pyridine

2: palladium diacetate; ammonium peroxydisulfate; trifluorormethanesulfonic acid / 1,2-dichloro-ethane / 20 h / 20 °C / Sealed tube

With pyridine; selenium(IV) oxide; ammonium peroxydisulfate; trifluorormethanesulfonic acid; palladium diacetate; In 1,2-dichloro-ethane;

DOI:10.1002/adsc.201200993

upstream raw materials:

O-(4-chlorophenyl)-N,N-dimethylcarbamate

4-(trifluoromethyl)phenylglyoxylic acid

1-(4-trifluoromethylphenyl)ethanone