(R)-3-(4-fluorophenyl)-4-methyl-3-phenyl-2,3-dihydro-1,2,5-thiadiazole-1,1-dioxide

Base Information

Chemical Name:(R)-3-(4-fluorophenyl)-4-methyl-3-phenyl-2,3-dihydro-1,2,5-thiadiazole-1,1-dioxide
CAS No.:1620097-62-2
Molecular Formula:C₁₅H₁₃FN₂O₂S
Molecular Weight:304.345
Hs Code.:

Synonyms:(R)-3-(4-fluorophenyl)-4-methyl-3-phenyl-2,3-dihydro-1,2,5-thiadiazole-1,1-dioxide

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Chemical Property of (R)-3-(4-fluorophenyl)-4-methyl-3-phenyl-2,3-dihydro-1,2,5-thiadiazole-1,1-dioxide

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Technology Process of (R)-3-(4-fluorophenyl)-4-methyl-3-phenyl-2,3-dihydro-1,2,5-thiadiazole-1,1-dioxide

There total 1 articles about (R)-3-(4-fluorophenyl)-4-methyl-3-phenyl-2,3-dihydro-1,2,5-thiadiazole-1,1-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 1765-93-1
4-fluoroboronic acid

: 3775-21-1
3-methyl-4-phenyl-1,2,5-thiadiazole-1,1-dioxide

: 1620097-61-1
(R)-3-(4-fluorophenyl)-3-methyl-4-phenyl-2,3-dihydro-1,2,5-thiadiazole-1,1-dioxide

: 1620097-62-2
(R)-3-(4-fluorophenyl)-4-methyl-3-phenyl-2,3-dihydro-1,2,5-thiadiazole-1,1-dioxide

Guidance literature:: 4-fluoroboronic acid; 3-methyl-4-phenyl-1,2,5-thiadiazole-1,1-dioxide; With chlorobis(cyclooctene)rhodium(I) dimer; C₁₈H₂₃NOS; In dichloromethane; at 40 ℃; for 0.5h; Inert atmosphere;

With potassium fluoride; In dichloromethane; at 40 ℃; for 5h; enantioselective reaction; Inert atmosphere;
DOI:10.1021/ol501770q