N-(tert-butoxycarbonyl)-(L)-valine (S)-1-phenylethylthioamide

Base Information

Chemical Name:N-(tert-butoxycarbonyl)-(L)-valine (S)-1-phenylethylthioamide
CAS No.:915793-69-0
Molecular Formula:C₁₈H₂₈N₂O₂S
Molecular Weight:336.499
Hs Code.:

Synonyms:N-(tert-butoxycarbonyl)-(L)-valine (S)-1-phenylethylthioamide

Suppliers and Price of N-(tert-butoxycarbonyl)-(L)-valine (S)-1-phenylethylthioamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of N-(tert-butoxycarbonyl)-(L)-valine (S)-1-phenylethylthioamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of N-(tert-butoxycarbonyl)-(L)-valine (S)-1-phenylethylthioamide

There total 3 articles about N-(tert-butoxycarbonyl)-(L)-valine (S)-1-phenylethylthioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 137894-06-5
[(S)-2-methyl-1-((R)-1-phenyl-ethylcarbamoyl)-propyl]-carbamic acid tert-butyl ester

: 915793-69-0
N-(tert-butoxycarbonyl)-(L)-valine (S)-1-phenylethylthioamide

Guidance literature:: With Lawessons reagent; In tetrahydrofuran; at 60 ℃; for 8h;
DOI:10.1021/ol062227q

Reference yield:

: 13734-41-3
t-Boc-L-valine

: 915793-69-0
N-(tert-butoxycarbonyl)-(L)-valine (S)-1-phenylethylthioamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: isobutyl chloroformate; N-methylmorpholine / tetrahydrofuran / 1 h / -15 °C

1.2: 97 percent / tetrahydrofuran / 3 h / 20 °C

2.1: 77 percent / Lawesson's reagent / tetrahydrofuran / 8 h / 60 °C

With Lawessons reagent; 4-methyl-morpholine; isobutyl chloroformate; In tetrahydrofuran;
DOI:10.1021/ol062227q

Reference yield:

: 2627-86-3
(S)-1-phenyl-ethylamine

: 915793-69-0
N-(tert-butoxycarbonyl)-(L)-valine (S)-1-phenylethylthioamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: isobutyl chloroformate; N-methylmorpholine / tetrahydrofuran / 1 h / -15 °C

1.2: 97 percent / tetrahydrofuran / 3 h / 20 °C

2.1: 77 percent / Lawesson's reagent / tetrahydrofuran / 8 h / 60 °C

With Lawessons reagent; 4-methyl-morpholine; isobutyl chloroformate; In tetrahydrofuran;
DOI:10.1021/ol062227q