Pyrogallol Red

Base Information

• Chemical Name: Pyrogallol Red
• CAS No.: 32638-88-3
• Deprecated CAS: 116239-00-0,3172-49-4,205682-71-9,801145-40-4,810024-92-1,856926-05-1,205682-71-9,3172-49-4,801145-40-4,810024-92-1,856926-05-1
• Molecular Formula: C19H12O8S
• Molecular Weight: 400.365
• Hs Code.: 2934 99 90
• European Community (EC) Number: 251-134-3
• DSSTox Substance ID: DTXSID6067703
• Nikkaji Number: J208.860F
• Wikidata: Q1636128
• ChEMBL ID: CHEMBL3692123
• Mol file: 32638-88-3.mol

Synonyms:pyrogallol red;pyrogallol sulfonphthalein;pyrogallolsulfonephthalein

Chemical Property of Pyrogallol Red

Chemical Property:

• Appearance/Colour: dark brown powder
• Vapor Pressure: 10 mm Hg ( 167.7 °C)
• Melting Point: 133-134 °C(lit.)
• Refractive Index: n20/D 1.387
• Boiling Point: 686.1 °C at 760 mmHg
• PKA: 7.86±0.20(Predicted)
• Flash Point: 368.8 °C
• PSA: 141.90000
• Density: 1.082 g/mL at 20 °C
• LogP: 3.70630
• Storage Temp.: Store at +5°C to +30°C.
• Water Solubility.: Soluble in water, ammonium hydroxide (10 mg/ml), and ethanol.
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 0
• Exact Mass: 400.02528851
• Heavy Atom Count: 28
• Complexity: 690

Purity/Quality:

98%,99%, ^*data from raw suppliers

Pyrogallol Red ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn,Xi
• Statements: 20/21/22-52/53-68-36/37/38
• Safety Statements: 36/37-61-24/25-22-36-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3(C4=C(C(=C(C=C4)O)O)OC5=C3C=CC(=C5O)O)OS2(=O)=O
• Uses: The white powdery crystal was made by the superheating of gallic acid. Pyrogallic acid, popularly known as pyro, is one of the earliest developers and its use has spanned three centuries. It was first used in an acid state to physically develop wet collodion negatives. When silver bromide gelatin plates were adopted pyro was used again but in an alkaline state for chemical development. It was used throughout the 20th century and often chosen for the peculiar yellow stain it imparted to gelatin negatives. Pyrogallol Red is a complexometric indicator for the metal elements molybdenum and copper. Dyes and metabolites.

Technology Process of Pyrogallol Red

There total 2 articles about Pyrogallol Red which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

2-sulfobenzoic acid cyclic anhydride (81-08-3) + 2-hydroxyresorcinol (87-66-1) → pyrogallol red (32638-88-3,3172-49-4)

Guidance literature:

In xylene; for 0.00416667h; Microwave irradiation;

DOI:10.1135/cccc20021779

Reference yield:

2-hydroxyresorcinol (87-66-1) → pyrogallol red (32638-88-3,3172-49-4)

Guidance literature:

With xylene; unter Entfernen des entstehenden Wassers;

upstream raw materials:

2-sulfobenzoic acid cyclic anhydride

2-hydroxyresorcinol

Refernces

• 1、 Cihelnik, Simon,Stibor, Ivan,Lhotak, Pavel. "Solvent-free synthesis of sulfonephthaleins, sulfonefluoresceins and fluoresceins under microwave irradiation". . p. 1779 - 1789. Retrieved 2007/10/03.