N-(3-(4-chlorophenyl)-1-phenylprop-2-ynylidene) (4-fluorophenyl)methanamine

Base Information

Chemical Name:N-(3-(4-chlorophenyl)-1-phenylprop-2-ynylidene) (4-fluorophenyl)methanamine
CAS No.:1371579-48-4
Molecular Formula:C₂₂H₁₅ClFN
Molecular Weight:347.819
Hs Code.:

Synonyms:N-(3-(4-chlorophenyl)-1-phenylprop-2-ynylidene) (4-fluorophenyl)methanamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(3-(4-chlorophenyl)-1-phenylprop-2-ynylidene) (4-fluorophenyl)methanamine

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Technology Process of N-(3-(4-chlorophenyl)-1-phenylprop-2-ynylidene) (4-fluorophenyl)methanamine

There total 1 articles about N-(3-(4-chlorophenyl)-1-phenylprop-2-ynylidene) (4-fluorophenyl)methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 873-73-4
4-n-chlorophenylacetylene

: 88284-48-4
2-(trimethylsilyl)phenyl trifluoromethanesulfonate

: 148890-53-3
4-fluorobenzyl isocyanide

: 1371579-48-4
N-(3-(4-chlorophenyl)-1-phenylprop-2-ynylidene) (4-fluorophenyl)methanamine

Guidance literature:: With potassium fluoride; 18-crown-6 ether; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1021/jo300072x

Reference yield: 74.0%

: 1371579-48-4
N-(3-(4-chlorophenyl)-1-phenylprop-2-ynylidene) (4-fluorophenyl)methanamine

: 536-74-3
phenylacetylene

: 1371579-71-3
3-(4-chlorobenzyl)-6-(4-fluorophenyl)-2,5-diphenylpyridine

Guidance literature:: phenylacetylene; With caesium carbonate; In toluene; acetonitrile; at 20 - 75 ℃; Inert atmosphere;

N-(3-(4-chlorophenyl)-1-phenylprop-2-ynylidene) (4-fluorophenyl)methanamine; In toluene; acetonitrile; at 75 ℃; regioselective reaction; Inert atmosphere;
DOI:10.1021/jo300072x