C₁₈H₁₆BrNO₂

Base Information

Chemical Name:C₁₈H₁₆BrNO₂
CAS No.:1423703-51-8
Molecular Formula:C₁₈H₁₆BrNO₂
Molecular Weight:358.235
Hs Code.:

C<sub>18</sub>H<sub>16</sub>BrNO<sub>2</sub>

Synonyms:C₁₈H₁₆BrNO₂

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Chemical Property of C₁₈H₁₆BrNO₂

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Technology Process of C₁₈H₁₆BrNO₂

There total 3 articles about C₁₈H₁₆BrNO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.6%

: 589-87-7
1,4-bromoiodobenzene

: 945549-22-4
C₁₈H₂₄BNO₄

: 1423703-51-8
C₁₈H₁₆BrNO₂

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate; In 1,2-dimethoxyethane; water; at 80 ℃; Inert atmosphere;

Reference yield:

: 10075-50-0
5-bromo-1H-indole

: 1423703-51-8
C₁₈H₁₆BrNO₂

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C

1.2: 20 °C

2.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 4 h / Reflux; Inert atmosphere

3.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / water; 1,2-dimethoxyethane / 80 °C / Inert atmosphere

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; sodium hydride; sodium carbonate; In tetrahydrofuran; 1,2-dimethoxyethane; water;

Reference yield:

: 726174-45-4
ethyl 2-(5-bromo-1H-indol-1-yl)acetate

: 1423703-51-8
C₁₈H₁₆BrNO₂

Guidance literature:: Multi-step reaction with 2 steps

1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 4 h / Reflux; Inert atmosphere

2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / water; 1,2-dimethoxyethane / 80 °C / Inert atmosphere

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; sodium carbonate; In 1,2-dimethoxyethane; water;