1-{3-[5-(4-trifluoromethyl-phenyl)-thiophen-2-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy}-cyclopropanecarboxylic acid methyl ester

Base Information

Chemical Name:1-{3-[5-(4-trifluoromethyl-phenyl)-thiophen-2-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy}-cyclopropanecarboxylic acid methyl ester
CAS No.:952710-78-0
Molecular Formula:C₂₇H₂₆F₃NO₃S
Molecular Weight:501.57
Hs Code.:

1-{3-[5-(4-trifluoromethyl-phenyl)-thiophen-2-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy}-cyclopropanecarboxylic acid methyl ester

Synonyms:1-{3-[5-(4-trifluoromethyl-phenyl)-thiophen-2-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy}-cyclopropanecarboxylic acid methyl ester

Suppliers and Price of 1-{3-[5-(4-trifluoromethyl-phenyl)-thiophen-2-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy}-cyclopropanecarboxylic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-{3-[5-(4-trifluoromethyl-phenyl)-thiophen-2-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy}-cyclopropanecarboxylic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-{3-[5-(4-trifluoromethyl-phenyl)-thiophen-2-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy}-cyclopropanecarboxylic acid methyl ester

There total 1 articles about 1-{3-[5-(4-trifluoromethyl-phenyl)-thiophen-2-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy}-cyclopropanecarboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 952710-77-9
4-methanesulfonyloxy-2-{3-[5-(4-trifluoromethyl-phenyl)-thiophen-2-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy}-butyric acid methyl ester

: 952710-78-0
1-{3-[5-(4-trifluoromethyl-phenyl)-thiophen-2-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy}-cyclopropanecarboxylic acid methyl ester

Guidance literature:: 4-methanesulfonyloxy-2-{3-[5-(4-trifluoromethyl-phenyl)-thiophen-2-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy}-butyric acid methyl ester; With potassium tert-butylate; In tetrahydrofuran; at 0 ℃; for 1h;

With hydrogenchloride; In tetrahydrofuran; water; pH=4;

Reference yield: 33.0%

: 952710-78-0
1-{3-[5-(4-trifluoromethyl-phenyl)-thiophen-2-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy}-cyclopropanecarboxylic acid methyl ester

: 1-{3-[5-(4-trifluoromethyl-phenyl)-thiophen-2-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy}-cyclopropanecarboxylic acid

Guidance literature:: 1-{3-[5-(4-trifluoromethyl-phenyl)-thiophen-2-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy}-cyclopropanecarboxylic acid methyl ester; With methanol; sodium hydroxide; water; at 20 ℃;

With tartaric acid; In water; pH=3;