N-Benzooxazol-2-yl-3-(4-fluoro-phenyl)-2-(3-methanesulfonyl-phenyl)-propionamide

Base Information

Chemical Name:N-Benzooxazol-2-yl-3-(4-fluoro-phenyl)-2-(3-methanesulfonyl-phenyl)-propionamide
CAS No.:1380645-88-4
Molecular Formula:C₂₃H₁₉FN₂O₄S
Molecular Weight:438.479
Hs Code.:

Synonyms:N-Benzooxazol-2-yl-3-(4-fluoro-phenyl)-2-(3-methanesulfonyl-phenyl)-propionamide

Suppliers and Price of N-Benzooxazol-2-yl-3-(4-fluoro-phenyl)-2-(3-methanesulfonyl-phenyl)-propionamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-Benzooxazol-2-yl-3-(4-fluoro-phenyl)-2-(3-methanesulfonyl-phenyl)-propionamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-Benzooxazol-2-yl-3-(4-fluoro-phenyl)-2-(3-methanesulfonyl-phenyl)-propionamide

There total 4 articles about N-Benzooxazol-2-yl-3-(4-fluoro-phenyl)-2-(3-methanesulfonyl-phenyl)-propionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

: 4570-41-6
1,3-benzoxazol-2-amine

: 1380646-41-2
3-(4-fluoro-phenyl)-2-(3-methane-sulfonylphenyl)propionic acid

: 1380645-88-4
N-Benzooxazol-2-yl-3-(4-fluoro-phenyl)-2-(3-methanesulfonyl-phenyl)-propionamide

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃;

Reference yield:

: 847150-07-6
(3-methanesulfonylphenyl)acetic acid methyl ester

: 1380645-88-4
N-Benzooxazol-2-yl-3-(4-fluoro-phenyl)-2-(3-methanesulfonyl-phenyl)-propionamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 - 20 °C / Inert atmosphere

1.2: 2 h / 20 °C

2.1: potassium hydroxide; water / ethanol / 72 h / 20 °C

3.1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C

With dmap; water; sodium hydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; potassium hydroxide; In ethanol; dichloromethane; N,N-dimethyl-formamide; mineral oil;

Reference yield:

: 1380646-40-1
3-(4-fluoro-phenyl)-2-(3-methanesulfonylphenyl)-propionic acid methyl ester

: 1380645-88-4
N-Benzooxazol-2-yl-3-(4-fluoro-phenyl)-2-(3-methanesulfonyl-phenyl)-propionamide

Guidance literature:: Multi-step reaction with 2 steps

1: potassium hydroxide; water / ethanol / 72 h / 20 °C

2: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C

With dmap; water; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; potassium hydroxide; In ethanol; dichloromethane;