5-((2-(4-(benzyloxy)phenyl)-1H-benzo[d]imidazol-1-yl)methyl)-1,3,4-oxadiazole-2-thiol

Base Information

Chemical Name:5-((2-(4-(benzyloxy)phenyl)-1H-benzo[d]imidazol-1-yl)methyl)-1,3,4-oxadiazole-2-thiol
CAS No.:1002322-43-1
Molecular Formula:C₁₆H₁₁ClN₄OS
Molecular Weight:342.809
Hs Code.:

Synonyms:5-((2-(4-(benzyloxy)phenyl)-1H-benzo[d]imidazol-1-yl)methyl)-1,3,4-oxadiazole-2-thiol

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Chemical Property of 5-((2-(4-(benzyloxy)phenyl)-1H-benzo[d]imidazol-1-yl)methyl)-1,3,4-oxadiazole-2-thiol

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Technology Process of 5-((2-(4-(benzyloxy)phenyl)-1H-benzo[d]imidazol-1-yl)methyl)-1,3,4-oxadiazole-2-thiol

There total 5 articles about 5-((2-(4-(benzyloxy)phenyl)-1H-benzo[d]imidazol-1-yl)methyl)-1,3,4-oxadiazole-2-thiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 75-15-0,12122-00-8
carbon disulfide

: (2-(4-chlorophenyl)-1H-benzimidazol-1-yl)-acetic acid hydrazide

: 1002322-43-1
5-((2-(4-(benzyloxy)phenyl)-1H-benzo[d]imidazol-1-yl)methyl)-1,3,4-oxadiazole-2-thiol

Guidance literature:: With potassium hydroxide; In ethanol; water; for 3h; Heating;
DOI:10.1002/ardp.200700088

Reference yield:

: 95-54-5
1,2-diamino-benzene

: 1002322-43-1
5-((2-(4-(benzyloxy)phenyl)-1H-benzo[d]imidazol-1-yl)methyl)-1,3,4-oxadiazole-2-thiol

Guidance literature:: Multi-step reaction with 4 steps

1: N,N-dimethyl-formamide

2: potassium hydroxide / dimethyl sulfoxide

3: hydrazine hydrate / ethanol / 4 h / Reflux

4: potassium hydroxide / ethanol; water / 3 h / Reflux

With hydrazine hydrate; potassium hydroxide; In ethanol; water; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.3906/kim-1403-44

Reference yield:

: 104-88-1
4-chlorobenzaldehyde

: 1002322-43-1
5-((2-(4-(benzyloxy)phenyl)-1H-benzo[d]imidazol-1-yl)methyl)-1,3,4-oxadiazole-2-thiol

Guidance literature:: Multi-step reaction with 4 steps

1: N,N-dimethyl-formamide

2: potassium hydroxide / dimethyl sulfoxide

3: hydrazine hydrate / ethanol / 4 h / Reflux

4: potassium hydroxide / ethanol; water / 3 h / Reflux

With hydrazine hydrate; potassium hydroxide; In ethanol; water; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.3906/kim-1403-44