Technology Process of C45H70O11
There total 18 articles about C45H70O11 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
tetrabutyl ammonium fluoride;
In
tetrahydrofuran;
at 20 ℃;
DOI:10.1021/ol070517g
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: 3.19 g / CH2Cl2 / 12 h / 20 °C
2.1: 69 percent / oxygen; copper(II) acetate monohydrate / PdCl2 / N,N-dimethyl-acetamide; H2O / 12 h / 20 °C
3.1: ethyldiisopropylamine; dibutylboron triflate / CH2Cl2; diethyl ether / cooling
3.2: CH2Cl2; diethyl ether / cooling
3.3: 85 percent / aq. H2O2 / methanol; aq. phosphate buffer / pH 7
4.1: Et2BOMe / tetrahydrofuran; methanol / cooling
4.2: 76 percent / NaBH4 / methanol; tetrahydrofuran / cooling
5.1: 78 percent / ethyldiisopropyl amine / CHCl3 / Heating
6.1: aq. NaOH / tetrahydrofuran; methanol / 50 °C
7.1: tetrabutylammonium fluoride / tetrahydrofuran / 20 °C
With
sodium hydroxide; di-n-butylboryl trifluoromethanesulfonate; diethyl methoxy borane; tetrabutyl ammonium fluoride; oxygen; copper diacetate; N-ethyl-N,N-diisopropylamine;
palladium dichloride;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane; chloroform; N,N-dimethyl acetamide; water;
1.1: Wittig reaction / 2.1: Wacker reaction / 3.2: Evans aldol reaction;
DOI:10.1021/ol070517g
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 69 percent / oxygen; copper(II) acetate monohydrate / PdCl2 / N,N-dimethyl-acetamide; H2O / 12 h / 20 °C
2.1: ethyldiisopropylamine; dibutylboron triflate / CH2Cl2; diethyl ether / cooling
2.2: CH2Cl2; diethyl ether / cooling
2.3: 85 percent / aq. H2O2 / methanol; aq. phosphate buffer / pH 7
3.1: Et2BOMe / tetrahydrofuran; methanol / cooling
3.2: 76 percent / NaBH4 / methanol; tetrahydrofuran / cooling
4.1: 78 percent / ethyldiisopropyl amine / CHCl3 / Heating
5.1: aq. NaOH / tetrahydrofuran; methanol / 50 °C
6.1: tetrabutylammonium fluoride / tetrahydrofuran / 20 °C
With
sodium hydroxide; di-n-butylboryl trifluoromethanesulfonate; diethyl methoxy borane; tetrabutyl ammonium fluoride; oxygen; copper diacetate; N-ethyl-N,N-diisopropylamine;
palladium dichloride;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane; chloroform; N,N-dimethyl acetamide; water;
1.1: Wacker reaction / 2.2: Evans aldol reaction;
DOI:10.1021/ol070517g