(S)-2-(2,3-bis(dicyclohexylamino)cyclopropenimine)-3-phenylpropan-1-ol hydrochloride

Base Information

Chemical Name:(S)-2-(2,3-bis(dicyclohexylamino)cyclopropenimine)-3-phenylpropan-1-ol hydrochloride
CAS No.:1366421-67-1
Molecular Formula:C₃₆H₅₅N₃O*ClH
Molecular Weight:582.313
Hs Code.:

Synonyms:(S)-2-(2,3-bis(dicyclohexylamino)cyclopropenimine)-3-phenylpropan-1-ol hydrochloride

Suppliers and Price of (S)-2-(2,3-bis(dicyclohexylamino)cyclopropenimine)-3-phenylpropan-1-ol hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(S)-2-(2,3-Bis(dicyclohexylamino)cyclopropenimine)-3-phenylpropan-1-ol hydrochloride ≥95%
1g
$ 215.00

Sigma-Aldrich
(S)-2-(2,3-Bis(dicyclohexylamino)cyclopropenimine)-3-phenylpropan-1-ol hydrochloride ≥95%
500mg
$ 135.00

Total 2 raw suppliers

Chemical Property of (S)-2-(2,3-bis(dicyclohexylamino)cyclopropenimine)-3-phenylpropan-1-ol hydrochloride

Chemical Property:

Purity/Quality:

98%,99%, ^*data from raw suppliers

(S)-2-(2,3-Bis(dicyclohexylamino)cyclopropenimine)-3-phenylpropan-1-ol hydrochloride ≥95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Chiral cyclopropenimines are a highly effective new class of enantioselective Br?nsted base catalysts - the so-called “superbases” for enantioselective organocatalysis. Due to the prevalence of chemical reactions involving proton transfer as a key mechanistic event, Br?nsted bases have become indispensable tools for the practice of organic synthetic chemistry, capable of catalyzing proton transfer reactions enantioselectively for the production of optically enriched products. Catalyst is stored as co-salt for stability. Conversion of the HCl salt to free catalyst requires a simple wash with aqueous base. This is one of a suite of Br?nsted catalysts reported by Tristan Lambert and coworkers available through Sigma-Aldrich.

Technology Process of (S)-2-(2,3-bis(dicyclohexylamino)cyclopropenimine)-3-phenylpropan-1-ol hydrochloride

There total 2 articles about (S)-2-(2,3-bis(dicyclohexylamino)cyclopropenimine)-3-phenylpropan-1-ol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 6262-42-6
1,2,3,3-tetrachlorocyclopropene

: 3182-95-4
L-Phenylalaninol

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 1366421-67-1
(S)-2-(2,3-bis(dicyclohexylamino)cyclopropenimine)-3-phenylpropan-1-ol hydrochloride

Guidance literature:: 1,2,3,3-tetrachlorocyclopropene; N-cyclohexyl-cyclohexanamine; In dichloromethane; at 20 ℃; for 4h;

L-Phenylalaninol; In dichloromethane; at 20 ℃; for 10h;

With hydrogenchloride; In dichloromethane; water;
DOI:10.1021/ja3015764

Reference yield: 73.0%

: 6262-51-7
pentachlorocyclopropane

: 3182-95-4
L-Phenylalaninol

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 1366421-67-1
(S)-2-(2,3-bis(dicyclohexylamino)cyclopropenimine)-3-phenylpropan-1-ol hydrochloride

Guidance literature:: pentachlorocyclopropane; N-cyclohexyl-cyclohexanamine; In dichloromethane; at 20 ℃; for 48h;

L-Phenylalaninol; In dichloromethane; for 12h;

With hydrogenchloride; sodium sulfate; In dichloromethane; water;
DOI:10.1021/ja407277a