benzhydryl (1S,5R,6S)-1-(2-tert-butoxycarbonylaminoethyl)-2-(1,3,4-thiadiazol-2-yl)thiomethyl-6-<(1R)-1-triethylsilyloxyethyl>carbapen-2-em-3-carboxylate

Base Information

Chemical Name:benzhydryl (1S,5R,6S)-1-(2-tert-butoxycarbonylaminoethyl)-2-(1,3,4-thiadiazol-2-yl)thiomethyl-6-<(1R)-1-triethylsilyloxyethyl>carbapen-2-em-3-carboxylate
CAS No.:220430-21-7
Molecular Formula:C₃₈H₅₀N₄O₆S₂Si
Molecular Weight:751.056
Hs Code.:

benzhydryl (1S,5R,6S)-1-(2-tert-butoxycarbonylaminoethyl)-2-(1,3,4-thiadiazol-2-yl)thiomethyl-6-<(1R)-1-triethylsilyloxyethyl>carbapen-2-em-3-carboxylate

Synonyms:benzhydryl (1S,5R,6S)-1-(2-tert-butoxycarbonylaminoethyl)-2-(1,3,4-thiadiazol-2-yl)thiomethyl-6-<(1R)-1-triethylsilyloxyethyl>carbapen-2-em-3-carboxylate

Suppliers and Price of benzhydryl (1S,5R,6S)-1-(2-tert-butoxycarbonylaminoethyl)-2-(1,3,4-thiadiazol-2-yl)thiomethyl-6-<(1R)-1-triethylsilyloxyethyl>carbapen-2-em-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of benzhydryl (1S,5R,6S)-1-(2-tert-butoxycarbonylaminoethyl)-2-(1,3,4-thiadiazol-2-yl)thiomethyl-6-<(1R)-1-triethylsilyloxyethyl>carbapen-2-em-3-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of benzhydryl (1S,5R,6S)-1-(2-tert-butoxycarbonylaminoethyl)-2-(1,3,4-thiadiazol-2-yl)thiomethyl-6-<(1R)-1-triethylsilyloxyethyl>carbapen-2-em-3-carboxylate

There total 2 articles about benzhydryl (1S,5R,6S)-1-(2-tert-butoxycarbonylaminoethyl)-2-(1,3,4-thiadiazol-2-yl)thiomethyl-6-<(1R)-1-triethylsilyloxyethyl>carbapen-2-em-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 220430-20-6
benzhydryl (1S,5R,6S)-1-(2-azidoethyl)-2-(1,3,4-thiadiazol-2-yl)thiomethyl-6-<(1R)-1-triethylsilyloxyethyl>carbapen-2-em-3-carboxylate

: 220430-21-7
benzhydryl (1S,5R,6S)-1-(2-tert-butoxycarbonylaminoethyl)-2-(1,3,4-thiadiazol-2-yl)thiomethyl-6-<(1R)-1-triethylsilyloxyethyl>carbapen-2-em-3-carboxylate

Guidance literature:: With trimethylphosphane; In tetrahydrofuran; water; for 15h; Ambient temperature;
DOI:10.3987/COM-98-8302

Reference yield:

: 220430-46-6
(4S,5R,6S)-4-(2-Hydroxy-ethyl)-7-oxo-3-([1,3,4]thiadiazol-2-ylsulfanylmethyl)-6-((R)-1-triethylsilanyloxy-ethyl)-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid benzhydryl ester

: 220430-21-7
benzhydryl (1S,5R,6S)-1-(2-tert-butoxycarbonylaminoethyl)-2-(1,3,4-thiadiazol-2-yl)thiomethyl-6-<(1R)-1-triethylsilyloxyethyl>carbapen-2-em-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: triphenylphosphine, HN₃, diethyl azodicarboxylate / tetrahydrofuran; toluene / 1 h / 0 °C

2: 40 percent / trimethylphosphine / tetrahydrofuran; H₂O / 15 h / Ambient temperature

With tris-(2-chloro-ethyl)-amine; triphenylphosphine; diethylazodicarboxylate; trimethylphosphane; In tetrahydrofuran; water; toluene;
DOI:10.3987/COM-98-8302