C₂₂H₂₄O₅

Base Information

• Chemical Name: C₂₂H₂₄O₅
• CAS No.: 877168-04-2
• Molecular Formula: C₂₂H₂₄O₅
• Molecular Weight: 368.43
• Mol file: 877168-04-2.mol

Synonyms:C₂₂H₂₄O₅

Chemical Property of C₂₂H₂₄O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₂₂H₂₄O₅

There total 8 articles about C₂₂H₂₄O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

{[2-(bromomethyl)buta-2,3-dien-1-yl]oxymethyl}benzene (877168-03-1) + C19H32O4Si (877167-79-8) → C22H24O5 (877168-04-2)

Guidance literature:

With 4 A molecular sieve; silver trifluoroacetate; In dichloromethane; at -78 - 20 ℃;

DOI:10.1002/ejoc.200500609

Reference yield:

2-((benzyloxy)methyl)buta-2,3-dien-1-ol (877168-02-0) → C22H24O5 (877168-04-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: benzyl alcohol; Et₃N / CH₂Cl₂ / 0.5 h / 0 °C

1.2: LiBr / acetone / 0 - 20 °C

2.1: 60 percent / AgOCOCF₃; 4 Angstroem molecular sieves / CH₂Cl₂ / -78 - 20 °C

With 4 A molecular sieve; silver trifluoroacetate; triethylamine; benzyl alcohol; In dichloromethane; 2.1: Jefford coupling;

DOI:10.1002/ejoc.200500609

Reference yield:

benzyl 2-(hydroxymethyl)buta-2,3-dienoate (877167-87-8) → C22H24O5 (877168-04-2)

Guidance literature:

Multi-step reaction with 4 steps

1.1: 60 percent / TMSOTf / CH₂Cl₂ / 0 - 20 °C

2.1: DIBAL-H / toluene; CH₂Cl₂ / 2 h / -78 °C

3.1: benzyl alcohol; Et₃N / CH₂Cl₂ / 0.5 h / 0 °C

3.2: LiBr / acetone / 0 - 20 °C

4.1: 60 percent / AgOCOCF₃; 4 Angstroem molecular sieves / CH₂Cl₂ / -78 - 20 °C

With trimethylsilyl trifluoromethanesulfonate; 4 A molecular sieve; silver trifluoroacetate; diisobutylaluminium hydride; triethylamine; benzyl alcohol; In dichloromethane; toluene; 4.1: Jefford coupling;

DOI:10.1002/ejoc.200500609

upstream raw materials:

{[2-(bromomethyl)buta-2,3-dien-1-yl]oxymethyl}benzene

C₁₉H₃₂O₄Si

2-((benzyloxy)methyl)buta-2,3-dien-1-ol

benzyl 2-(hydroxymethyl)buta-2,3-dienoate