9-allyloxy-6-chloro-3-methyl-2,3,4,5-tetrahydro-1H-benzazepine

Base Information

Chemical Name:9-allyloxy-6-chloro-3-methyl-2,3,4,5-tetrahydro-1H-benzazepine
CAS No.:86120-57-2
Molecular Formula:C₁₄H₁₈ClNO
Molecular Weight:251.756
Hs Code.:2933990090
Mol file:86120-57-2.mol

Synonyms:6-allyloxy-9-chloro-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine;9-Allyloxy-6-chloro-3-methyl-2,3,4,5-tetrahydro-1H-benzazepine;9-(allyloxy)-6-chloro-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine;

Suppliers and Price of 9-allyloxy-6-chloro-3-methyl-2,3,4,5-tetrahydro-1H-benzazepine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 9-allyloxy-6-chloro-3-methyl-2,3,4,5-tetrahydro-1H-benzazepine

Chemical Property:

Vapor Pressure:9.19E-06mmHg at 25°C
Boiling Point:373.1°Cat760mmHg
Flash Point:179.4°C
PSA：21.26000
Density:1.098g/cm³
LogP:4.03700

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 9-allyloxy-6-chloro-3-methyl-2,3,4,5-tetrahydro-1H-benzazepine

There total 5 articles about 9-allyloxy-6-chloro-3-methyl-2,3,4,5-tetrahydro-1H-benzazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 78495-50-8
6-chloro-3-methyl-9-nitro-2,3,4,5-tetrahydro-1H-3-benzazepine

: 86120-57-2
9-allyloxy-6-chloro-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / hydrazine hydrate / Raney nickel / ethanol

2: 1.) sodium nitrite, aq. H₂SO₄, 2.) ammonium hydroxide / 1.) 1 h, 2.) water

3: 1.) NaH / 1.) DMF, 2.) DMF, RT, 20 h

With ammonium hydroxide; sulfuric acid; sodium hydride; hydrazine hydrate; sodium nitrite; nickel; In ethanol;
DOI:10.1021/jm00373a018

Reference yield:

: 73943-10-9
SKF 86466

: 86120-57-2
9-allyloxy-6-chloro-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

Guidance literature:: Multi-step reaction with 4 steps

1: 44 percent / conc. nitric acid, conc. H₂SO₄ / Ambient temperature

2: 95 percent / hydrazine hydrate / Raney nickel / ethanol

3: 1.) sodium nitrite, aq. H₂SO₄, 2.) ammonium hydroxide / 1.) 1 h, 2.) water

4: 1.) NaH / 1.) DMF, 2.) DMF, RT, 20 h

With ammonium hydroxide; sulfuric acid; nitric acid; sodium hydride; hydrazine hydrate; sodium nitrite; nickel; In ethanol;
DOI:10.1021/jm00373a018

Reference yield:

: 78495-53-1
9-amino-6-chloro-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

: 86120-57-2
9-allyloxy-6-chloro-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) sodium nitrite, aq. H₂SO₄, 2.) ammonium hydroxide / 1.) 1 h, 2.) water

2: 1.) NaH / 1.) DMF, 2.) DMF, RT, 20 h

With ammonium hydroxide; sulfuric acid; sodium hydride; sodium nitrite;
DOI:10.1021/jm00373a018