(1S,3R)-2,2-dimethyl-3-(2-(2-methyl-1,3-dioxolan-2-yl)ethyl)-4-methylenecyclohexanol

Base Information

• Chemical Name: (1S,3R)-2,2-dimethyl-3-(2-(2-methyl-1,3-dioxolan-2-yl)ethyl)-4-methylenecyclohexanol
• CAS No.: 1020736-17-7
• Molecular Formula: C₁₅H₂₆O₃
• Molecular Weight: 254.37
• Mol file: 1020736-17-7.mol

Synonyms:(1S,3R)-2,2-dimethyl-3-(2-(2-methyl-1,3-dioxolan-2-yl)ethyl)-4-methylenecyclohexanol

Chemical Property of (1S,3R)-2,2-dimethyl-3-(2-(2-methyl-1,3-dioxolan-2-yl)ethyl)-4-methylenecyclohexanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1S,3R)-2,2-dimethyl-3-(2-(2-methyl-1,3-dioxolan-2-yl)ethyl)-4-methylenecyclohexanol

There total 5 articles about (1S,3R)-2,2-dimethyl-3-(2-(2-methyl-1,3-dioxolan-2-yl)ethyl)-4-methylenecyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

C17H28O4 (1123890-01-6) → (1S,3R)-2,2-dimethyl-3-(2-(2-methyl-1,3-dioxolan-2-yl)ethyl)-4-methylenecyclohexanol (1020736-17-7)

Guidance literature:

With potassium carbonate; In methanol; at 20 ℃; for 7h; optical yield given as %ee;

DOI:10.1002/adsc.200700511

Reference yield: 77.0%

2-methyl-2-((E)-4-methyl-6-(3,3-dimethyloxiran-2-yl)hex-3-enyl)-1,3-dioxolane (32247-48-6) → (1S,3R)-2,2-dimethyl-3-(2-(2-methyl-1,3-dioxolan-2-yl)ethyl)-4-methylenecyclohexanol (1020736-17-7)

Guidance literature:

With 2,4,6-trimethyl-pyridine; bis(cyclopentadienyl)titanium dichloride; manganese; tertiary butyl chloride; In tetrahydrofuran; for 2h;

DOI:10.1021/ol800326n

Reference yield:

C15H26O3 → (1S,3R)-2,2-dimethyl-3-(2-(2-methyl-1,3-dioxolan-2-yl)ethyl)-4-methylenecyclohexanol (1020736-17-7) + C15H26O3 (1123890-03-8)

Guidance literature:

With 2,4,6-trimethyl-pyridine; bis(cyclopentadienyl)titanium dichloride; manganese; chloro-trimethyl-silane; In tetrahydrofuran; at 20 ℃; for 1.5h; optical yield given as %ee; diastereoselective reaction; Inert atmosphere;

DOI:10.1002/adsc.200700511

upstream raw materials:

2-methyl-2-((E)-4-methyl-6-(3,3-dimethyloxiran-2-yl)hex-3-enyl)-1,3-dioxolane

C₁₇H₂₈O₄

trans geranyl acetone

(5E)-6,10-dimethylundeca-5,9-dien-2-one ethylene acetal

Downstream raw materials:

C₁₃H₂₂O₂

C₂₂H₂₅F₅O₄S

C₁₇H₂₈O₄