4-(3-((4-(2-fluoro-4-nitrophenoxy)-6-methoxyquinolin-7-yl)oxy)propyl)morpholine

Base Information

Chemical Name:4-(3-((4-(2-fluoro-4-nitrophenoxy)-6-methoxyquinolin-7-yl)oxy)propyl)morpholine
CAS No.:960299-44-9
Molecular Formula:C₂₃H₂₄FN₃O₆
Molecular Weight:457.458
Hs Code.:

Synonyms:4-(3-((4-(2-fluoro-4-nitrophenoxy)-6-methoxyquinolin-7-yl)oxy)propyl)morpholine

Suppliers and Price of 4-(3-((4-(2-fluoro-4-nitrophenoxy)-6-methoxyquinolin-7-yl)oxy)propyl)morpholine

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Chemical Property of 4-(3-((4-(2-fluoro-4-nitrophenoxy)-6-methoxyquinolin-7-yl)oxy)propyl)morpholine

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Technology Process of 4-(3-((4-(2-fluoro-4-nitrophenoxy)-6-methoxyquinolin-7-yl)oxy)propyl)morpholine

There total 28 articles about 4-(3-((4-(2-fluoro-4-nitrophenoxy)-6-methoxyquinolin-7-yl)oxy)propyl)morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 479690-08-9
1-(2-fluoro-4-nitrophenyl)-6-hydroxy-7-methoxy-quinoline

: 57616-74-7
N-(3-chloropropyl)morpholine hydrochloride

: 960299-44-9
4-(3-((4-(2-fluoro-4-nitrophenoxy)-6-methoxyquinolin-7-yl)oxy)propyl)morpholine

Guidance literature:: With caesium carbonate; potassium iodide; In acetonitrile; at 20 ℃; for 3.75h; Reflux;
DOI:10.1021/acs.jmedchem.8b00672

Reference yield: 77.0%

: 4441-30-9
3-morpholin-4-ylpropan-1-ol

: 479690-08-9
1-(2-fluoro-4-nitrophenyl)-6-hydroxy-7-methoxy-quinoline

: 960299-44-9
4-(3-((4-(2-fluoro-4-nitrophenoxy)-6-methoxyquinolin-7-yl)oxy)propyl)morpholine

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In dichloromethane; at 20 ℃;

Reference yield: 77.0%

: 479690-08-9
1-(2-fluoro-4-nitrophenyl)-6-hydroxy-7-methoxy-quinoline

: 960299-44-9
4-(3-((4-(2-fluoro-4-nitrophenoxy)-6-methoxyquinolin-7-yl)oxy)propyl)morpholine

Guidance literature:: 1-(2-fluoro-4-nitrophenyl)-6-hydroxy-7-methoxy-quinoline; With potassium carbonate; at 20 ℃; for 0.5h;

(3-halopropyl)morpholine; at 70 ℃; for 4h;
DOI:10.1016/j.ejmech.2020.112174