2,3-dimethoxy-6-(4-methoxy-7-methyl-8,9-dihydro-7H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]azepin-6-yl)-benzoic acid; sodium salt

Base Information

• Chemical Name: 2,3-dimethoxy-6-(4-methoxy-7-methyl-8,9-dihydro-7H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]azepin-6-yl)-benzoic acid; sodium salt
• CAS No.: 33529-29-2
• Molecular Formula: C₂₂H₂₂NO₇*Na
• Molecular Weight: 435.409
• Mol file: 33529-29-2.mol

Synonyms:2,3-dimethoxy-6-(4-methoxy-7-methyl-8,9-dihydro-7H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]azepin-6-yl)-benzoic acid; sodium salt

Chemical Property of 2,3-dimethoxy-6-(4-methoxy-7-methyl-8,9-dihydro-7H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]azepin-6-yl)-benzoic acid; sodium salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-dimethoxy-6-(4-methoxy-7-methyl-8,9-dihydro-7H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]azepin-6-yl)-benzoic acid; sodium salt

There total 1 articles about 2,3-dimethoxy-6-(4-methoxy-7-methyl-8,9-dihydro-7H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]azepin-6-yl)-benzoic acid; sodium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2N-NaOH + 2,3-dimethoxy-6-(2-methoxy-3,4-methylenedioxy-6-methylaminoethylphenylacetyl)benzoic acid ethyl ester hydrochloride → 2,3-dimethoxy-6-(7-methyl-8,9-dihydro-7H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]azepin-6-yl)-benzoic acid; sodium salt (39650-50-5) + 2,3-dimethoxy-6-(4-methoxy-7-methyl-8,9-dihydro-7H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]azepin-6-yl)-benzoic acid; sodium salt (33529-29-2)

Guidance literature:

Reference yield:

2,3-dimethoxy-6-(4-methoxy-7-methyl-8,9-dihydro-7H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]azepin-6-yl)-benzoic acid; sodium salt (33529-29-2) → 2,3-dimethoxy-6-{[4-methoxy-6-(2-methylamino-ethyl)-benzo[1,3]dioxol-5-yl]-acetyl}-benzoic acid (483-89-6)

Guidance literature:

With hydrogenchloride; In water;

Reference yield:

2,3-dimethoxy-6-(4-methoxy-7-methyl-8,9-dihydro-7H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]azepin-6-yl)-benzoic acid; sodium salt (33529-29-2) → 9,10,14-trimethoxy-5,6,12b,13-tetrahydro-[1,3]dioxolo[4'',5'':4',5']benzo[1',2':4,5]azepino[2,1-a]isoindol-8-one (50347-54-1)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) AcOH, (ii) LiBH₄, THF

2: acetic anhydride

In acetic anhydride;

DOI:10.1139/v72-325

Downstream raw materials:

2,3-dimethoxy-6-(4-methoxy-7-methyl-6,7,8,9-tetrahydro-5H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]azepin-6-yl)-benzoic acid

9,10,14-trimethoxy-5,6,12b,13-tetrahydro-[1,3]dioxolo[4'',5'':4',5']benzo[1',2':4,5]azepino[2,1-a]isoindol-8-one

2,3-dimethoxy-6-{[4-methoxy-6-(2-methylamino-ethyl)-benzo[1,3]dioxol-5-yl]-acetyl}-benzoic acid