C₄₉H₅₁NO₁₅

Base Information

• Chemical Name: C₄₉H₅₁NO₁₅
• CAS No.: 860782-70-3
• Molecular Formula: C₄₉H₅₁NO₁₅
• Molecular Weight: 893.942
• Mol file: 860782-70-3.mol

Synonyms:C₄₉H₅₁NO₁₅

Chemical Property of C₄₉H₅₁NO₁₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₉H₅₁NO₁₅

There total 15 articles about C₄₉H₅₁NO₁₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

C64H85NO15Si2 (860782-69-0) → C49H51NO15 (860782-70-3)

Guidance literature:

With pyridine hydrogenfluoride; In tetrahydrofuran; at 0 - 20 ℃;

Reference yield:

(3-allyloxy-benzylidene)-(4-methoxy-phenyl)-amine → C49H51NO15 (860782-70-3)

Guidance literature:

Multi-step reaction with 9 steps

1: 75 percent / i-Pr₂NEt / CH₂Cl₂ / 12 h / -78 - 20 °C

2: 48 percent / lipase PS / aq. phosphate buffer; acetonitrile / 74 h / 20 °C / pH 7

3: 99 percent / aq. KOH / tetrahydrofuran / 0.25 h

4: 1.15 g / imidazole / dimethylformamide / 8 h / 20 °C

5: 78 percent / aq. ceric ammonium nitrate / acetonitrile / 1.08 h / 0 °C

6: 82 percent / dimethylaminopyridine / CH₂Cl₂ / 1 h / 0 °C

7: 65 percent / lithium hexamethyldisilazide / tetrahydrofuran / 3 h / -40 °C

8: 65 percent / (H₂IMes)(PCy₃)(Cl)2Ru=CHPh / CH₂Cl₂ / 4 h / 20 °C

9: 91 percent / HF*pyridine / tetrahydrofuran / 0 - 20 °C

With 1H-imidazole; dmap; potassium hydroxide; ammonium cerium(IV) nitrate; Lipase PS; pyridine hydrogenfluoride; N-ethyl-N,N-diisopropylamine; lithium hexamethyldisilazane; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In tetrahydrofuran; phosphate buffer; dichloromethane; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1021/jm061071x

Reference yield:

4-deacetyl-4-acryloylbaccatin III (860782-21-4) → C49H51NO15 (860782-70-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 72 percent / imidazole / CH₂Cl₂ / 3 h / 0 °C

2: 65 percent / lithium hexamethyldisilazide / tetrahydrofuran / 3 h / -40 °C

3: 65 percent / (H₂IMes)(PCy₃)(Cl)2Ru=CHPh / CH₂Cl₂ / 4 h / 20 °C

4: 91 percent / HF*pyridine / tetrahydrofuran / 0 - 20 °C

With 1H-imidazole; pyridine hydrogenfluoride; lithium hexamethyldisilazane; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In tetrahydrofuran; dichloromethane;

DOI:10.1021/jm061071x

upstream raw materials:

C₆₄H₈₅NO₁₅Si₂

4-deacetyl-4-acryloyl-10-deacetylbaccatin III

4-deacetyl-4-acryloylbaccatin III

4-deacetyl-4-acryloyl-7-O-triethylsilylbaccatin III