(S)-1-(ortho-chlorophenyl)ethyl (R)-α-methoxy-α-trifluoromethylphenylacetate

Base Information

Chemical Name:(S)-1-(ortho-chlorophenyl)ethyl (R)-α-methoxy-α-trifluoromethylphenylacetate
CAS No.:131864-75-0
Molecular Formula:C₁₈H₁₆ClF₃O₃
Molecular Weight:372.771
Hs Code.:

Synonyms:(S)-1-(ortho-chlorophenyl)ethyl (R)-α-methoxy-α-trifluoromethylphenylacetate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-1-(ortho-chlorophenyl)ethyl (R)-α-methoxy-α-trifluoromethylphenylacetate

Chemical Property:

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Technology Process of (S)-1-(ortho-chlorophenyl)ethyl (R)-α-methoxy-α-trifluoromethylphenylacetate

There total 2 articles about (S)-1-(ortho-chlorophenyl)ethyl (R)-α-methoxy-α-trifluoromethylphenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13524-04-4,120466-66-2,132437-66-2,131864-71-6
(S)-1-(2'-chlorophenyl)ethanol

: 39637-99-5,20445-33-4
(S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride

: 131864-75-0
(S)-1-(ortho-chlorophenyl)ethyl (R)-α-methoxy-α-trifluoromethylphenylacetate

Guidance literature:: With dmap; triethylamine; In dichloromethane;
DOI:10.1039/c1ob05510k

Reference yield:

: 2142-68-9
1-(2-chlorophenyl)ethanone

: 131864-75-0
(S)-1-(ortho-chlorophenyl)ethyl (R)-α-methoxy-α-trifluoromethylphenylacetate

Guidance literature:: Multi-step reaction with 2 steps

1: Candida tenuis AKR₂B₅ xylose reductase [E_.⁽¹⁾C₁₁₁₇₅]; water; NADH / ethanol / 25 °C / pH 7 / aq. phosphate buffer; Enzymatic reaction

2: dmap; triethylamine / dichloromethane

With dmap; Candida tenuis AKR₂B₅ xylose reductase [E_.⁽¹⁾C₁₁₁₇₅]; water; triethylamine; NADH; In ethanol; dichloromethane;
DOI:10.1039/c1ob05510k