(3S,8aR)-2-benzyl-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]octahydropyrrolo[1,2-a]pyrazine-3-carboxamide

Base Information

Chemical Name:(3S,8aR)-2-benzyl-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]octahydropyrrolo[1,2-a]pyrazine-3-carboxamide
CAS No.:1266229-40-6
Molecular Formula:C₂₅H₃₁N₃O
Molecular Weight:389.541
Hs Code.:

Synonyms:(3S,8aR)-2-benzyl-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]octahydropyrrolo[1,2-a]pyrazine-3-carboxamide

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Chemical Property of (3S,8aR)-2-benzyl-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]octahydropyrrolo[1,2-a]pyrazine-3-carboxamide

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Technology Process of (3S,8aR)-2-benzyl-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]octahydropyrrolo[1,2-a]pyrazine-3-carboxamide

There total 1 articles about (3S,8aR)-2-benzyl-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]octahydropyrrolo[1,2-a]pyrazine-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₅H₂₀N₂O₂

: 23357-46-2
(R)-1,2,3,4-Tetrahydro-1-naphthylamine

: 1266229-40-6
(3S,8aR)-2-benzyl-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]octahydropyrrolo[1,2-a]pyrazine-3-carboxamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 6h;

Reference yield:

: 1266229-40-6
(3S,8aR)-2-benzyl-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]octahydropyrrolo[1,2-a]pyrazine-3-carboxamide

: 1266229-41-7
(1R)-N-{[(3R,8aR)-2-benzyloctahydropyrrolo[1,2-a]pyrazin-3-yl]methyl}1,2,3,4-tetrahydronaphthalen-1-amine

Guidance literature:: (3S,8aR)-2-benzyl-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]octahydropyrrolo[1,2-a]pyrazine-3-carboxamide; With lithium aluminium tetrahydride; In tetrahydrofuran; at 70 ℃; for 24h; Cooling with ice;

With sodium hydroxide; In tetrahydrofuran; water; at 20 ℃;