Technology Process of 3-(((tert-butyldimethylsilyl)oxy)methyl)-4-methoxyaniline
There total 6 articles about 3-(((tert-butyldimethylsilyl)oxy)methyl)-4-methoxyaniline which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
palladium on activated charcoal; hydrogen;
In
methanol;
for 1.08333h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: dmap; triethylamine / dichloromethane / 2 h
2: palladium on activated charcoal; hydrogen / methanol / 1.08 h
With
dmap; palladium on activated charcoal; hydrogen; triethylamine;
In
methanol; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: zinc / N,N-dimethyl-formamide / 22 h / 90 °C / Inert atmosphere; Sealed tube
2: diisobutylaluminium hydride / 3.08 h / 0 - 20 °C / Inert atmosphere
3: diisobutylaluminium hydride / tetrahydrofuran; toluene / 1 h / -78 - 20 °C / Inert atmosphere
4: dmap; triethylamine / dichloromethane / 2 h
5: palladium on activated charcoal; hydrogen / methanol / 1.08 h
With
dmap; palladium on activated charcoal; hydrogen; diisobutylaluminium hydride; triethylamine; zinc;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; toluene;
1: |Suzuki-Miyaura Coupling;