N-Vinyl-2-pyrrolidone

Base Information

• Chemical Name: N-Vinyl-2-pyrrolidone
• CAS No.: 25249-54-1
• Deprecated CAS: 153631-60-8,94800-10-9,1229193-78-5,1229193-78-5,94800-10-9
• Molecular Formula: (C6H9NO)n
• Molecular Weight: 111.14200
• Hs Code.: 39059900
• European Community (EC) Number: 201-800-4,607-660-4,618-363-4,658-049-4,658-051-5
• ICSC Number: 1478
• NSC Number: 683040,142693,114022,10222
• UNII: 76H9G81541
• DSSTox Substance ID: DTXSID2021440
• Nikkaji Number: J36.503C
• Wikipedia: N-Vinylpyrrolidone
• Wikidata: Q420628
• NCI Thesaurus Code: C77491,C80893
• RXCUI: 1307764,8610,1310706
• ChEMBL ID: CHEMBL1878943
• Mol file: 25249-54-1.mol

Synonyms:1-vinyl-2-pyrrolidone;N- vinyl pyrrolidone;N-vinyl-2-pyrrolidinone;N-vinylpyrrolidone

Chemical Property of N-Vinyl-2-pyrrolidone

Chemical Property:

• Appearance/Colour: White to off-white micro-crystalline powder
• Vapor Pressure: 0.132mmHg at 25°C
• Melting Point: ~165 °C (dec.)(lit.)
• Refractive Index: 1.593
• Boiling Point: 217.6°C at 760 mmHg
• Flash Point: 93.9°C
• PSA: 60.93000
• Density: 1.144 g/cm³
• LogP: 1.44760
• Water Solubility.: Insoluble in water, acid and alkaline.
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 111.068413911
• Heavy Atom Count: 8
• Complexity: 120

Purity/Quality:

94% ^*data from raw suppliers

Poly(vinylpolypyrrolidone) ~110?μm particle size ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Plastics & Rubber -> Other Monomers,Plastics & Rubber -> Polymers
• Canonical SMILES: C=CN1CCCC1=O
• Recent ClinicalTrials: Efficacy and Safety Assessment of Azyter? Eye Drops (T1225) in Patients With Blepharitis
• Recent EU Clinical Trials: Can a sinus rinse and mouth wash reduce viral load in COVID-19 positive individuals?
• Recent NIPH Clinical Trials: Study on reduction of salivary virus by povidone iodine on COVID-19
• Inhalation Risk: A harmful contamination of the air will be reached quickly on evaporation of this substance at 20 °C.
• Effects of Short Term Exposure: The substance is corrosive to the eyes. The substance is irritating to the respiratory tract.
• Effects of Long Term Exposure: The substance may have effects on the liver. This may result in liver impairment. Tumours have been detected in experimental animals but may not be relevant to humans.
• Uses: PVP (polyvinylpyrrolidone) is a chemical ingredient that, depending on the formulatory requirement, can act as a binder, viscosity controller, emulsion stabilizer, or film former. Its benefits include water and wear resistance, pigment dispersion, a non-greasy feel, and improved stick integrity. PVP is commonly found in waterproof sunscreens, mascaras, and lipsticks in order to improve their wear. Polyvinylpyrrolidone (PVP) has been used as a clarifying agent in the food industry. Polyvinylpyrrolidone is used in coatings, printing ink, rubber, glass, leather, cosmetics, soaps, plastics, in paper making and as a stabilizer. It acts as a disintegrant in pharmaceutical tablets and as a fining to extract impurities. It is used to remove polyphenols in beer.