(S)-bis(4-methoxybenzyl)-2-(3-((R)-1-(4-methoxybenzyloxy)-3-(methylthio)-1-oxopropan-2-yl)ureido)pentanedioate

Base Information

• Chemical Name: (S)-bis(4-methoxybenzyl)-2-(3-((R)-1-(4-methoxybenzyloxy)-3-(methylthio)-1-oxopropan-2-yl)ureido)pentanedioate
• CAS No.: 1092539-90-6
• Molecular Formula: C₃₄H₄₀N₂O₁₀S
• Molecular Weight: 668.765
• Mol file: 1092539-90-6.mol

Synonyms:(S)-bis(4-methoxybenzyl)-2-(3-((R)-1-(4-methoxybenzyloxy)-3-(methylthio)-1-oxopropan-2-yl)ureido)pentanedioate

Chemical Property of (S)-bis(4-methoxybenzyl)-2-(3-((R)-1-(4-methoxybenzyloxy)-3-(methylthio)-1-oxopropan-2-yl)ureido)pentanedioate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (S)-bis(4-methoxybenzyl)-2-(3-((R)-1-(4-methoxybenzyloxy)-3-(methylthio)-1-oxopropan-2-yl)ureido)pentanedioate

There total 1 articles about (S)-bis(4-methoxybenzyl)-2-(3-((R)-1-(4-methoxybenzyloxy)-3-(methylthio)-1-oxopropan-2-yl)ureido)pentanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

bis(trichloromethyl) carbonate (32315-10-9) + (S)-1,5-bis((4-methoxybenzyl)oxy)-1,5-dioxopentan-2-aminium chloride (68709-64-8) + (R)-4-methoxybenzyl-2-amino-3-(methylthio)propionate (1092539-89-3) → (S)-bis(4-methoxybenzyl)-2-(3-((R)-1-(4-methoxybenzyloxy)-3-(methylthio)-1-oxopropan-2-yl)ureido)pentanedioate (1092539-90-6)

Guidance literature:

bis(trichloromethyl) carbonate; (S)-1,5-bis((4-methoxybenzyl)oxy)-1,5-dioxopentan-2-aminium chloride; With triethylamine; In dichloromethane; at -78 - 20 ℃; for 1.75h; Inert atmosphere;

(R)-4-methoxybenzyl-2-amino-3-(methylthio)propionate; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1021/jm800765e

upstream raw materials:

bis(trichloromethyl) carbonate

(S)-1,5-bis((4-methoxybenzyl)oxy)-1,5-dioxopentan-2-aminium chloride

(R)-4-methoxybenzyl-2-amino-3-(methylthio)propionate