1-(1,3-Benzodioxol-5-ylcarbonyl)piperidine

Base Information

Chemical Name:1-(1,3-Benzodioxol-5-ylcarbonyl)piperidine
CAS No.:34023-62-6
Molecular Formula:C₁₃H₁₅NO₃
Molecular Weight:233.267
Hs Code.:2934999090
DSSTox Substance ID:DTXSID10187634
Nikkaji Number:J624.924H
Wikidata:Q27188679
ChEMBL ID:CHEMBL103469
Mol file:34023-62-6.mol

Synonyms:1,3-BYCP;1-(1,3-benzodioxol-5-ylcarbonyl)piperidine;1-BCP;BA 14;BA-14

Suppliers and Price of 1-(1,3-Benzodioxol-5-ylcarbonyl)piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
1-BCP
10mg
$ 403.00

Usbiological
1-BCP
10mg
$ 382.00

TRC
1-BCP
10mg
$ 105.00

DC Chemicals
1-BCP >98%
1 g
$ 2200.00

DC Chemicals
1-BCP >98%
250 mg
$ 1100.00

ChemScene
1-BCP >99.0%
5mg
$ 190.00

American Custom Chemicals Corporation
1-BCP 95.00%
50MG
$ 1041.76

American Custom Chemicals Corporation
1-BCP 95.00%
10MG
$ 660.95

Total 14 raw suppliers

Chemical Property of 1-(1,3-Benzodioxol-5-ylcarbonyl)piperidine

Chemical Property:

Vapor Pressure:7.85E-07mmHg at 25°C
Boiling Point:406.9°Cat760mmHg
PKA:-1.10±0.20(Predicted)
Flash Point:199.9°C
PSA：38.77000
Density:1.256g/cm³
LogP:1.97930
Storage Temp.:Store at RT
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:233.10519334
Heavy Atom Count:17
Complexity:288

Purity/Quality:

99%, ^*data from raw suppliers

1-BCP ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(CC1)C(=O)C2=CC3=C(C=C2)OCO3
Uses 1-BCP is a centrally active selective potentiator of AMPA-mediated responses.

Technology Process of 1-(1,3-Benzodioxol-5-ylcarbonyl)piperidine

There total 4 articles about 1-(1,3-Benzodioxol-5-ylcarbonyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 110-89-4
piperidine

: 25054-53-9
3,4-(methylenedioxy)benzoyl chloride

: 34023-62-6
1-piperonyloyl-piperidine

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 16h; Inert atmosphere;
DOI:10.1021/jacs.1c04363

Reference yield: 83.0%

: 110-89-4
piperidine

: 102132-54-7
1,3-benzodioxole-5-carboxylic acid 2,5-dioxo-1-pyrrolidinyl ester

: 34023-62-6
1-piperonyloyl-piperidine

Guidance literature:: In dichloromethane; at 20 ℃; for 2h;
DOI:10.3390/molecules19011034

Reference yield:

: 94-53-1
Piperonylic acid

: 34023-62-6
1-piperonyloyl-piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / CH₂Cl₂ / 1 h / Heating

2: 85.5 percent / pyridine / 2 h / 0 °C

With thionyl chloride; In pyridine; dichloromethane;
DOI:10.1248/cpb.35.2437