C₂₈H₃₃FN₄O₃

Base Information

Chemical Name:C₂₈H₃₃FN₄O₃
CAS No.:870552-35-5
Molecular Formula:C₂₈H₃₃FN₄O₃
Molecular Weight:492.593
Hs Code.:

C<sub>28</sub>H<sub>33</sub>FN<sub>4</sub>O<sub>3</sub>

Synonyms:C₂₈H₃₃FN₄O₃

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₈H₃₃FN₄O₃

Chemical Property:

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Technology Process of C₂₈H₃₃FN₄O₃

There total 7 articles about C₂₈H₃₃FN₄O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 870545-64-5
C₃₅H₃₉FN₄O₃

: 870552-35-5
C₂₈H₃₃FN₄O₃

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol;
DOI:10.1016/j.bmcl.2013.03.125

Reference yield:

: 1480-87-1
2-fluoro-3-nitropyridine

: 870552-35-5
C₂₈H₃₃FN₄O₃

Guidance literature:: Multi-step reaction with 6 steps

1: potassium carbonate / N,N-dimethyl-formamide / 130 °C

2: hydrogen; palladium 10% on activated carbon / methanol; tetrahydrofuran

3: sodium hydrogencarbonate / dichloromethane

4: tetrahydrofuran

5: di-tert-butyl-diazodicarboxylate / tetrahydrofuran

6: hydrogen; palladium 10% on activated carbon / methanol

With di-tert-butyl-diazodicarboxylate; palladium 10% on activated carbon; hydrogen; sodium hydrogencarbonate; potassium carbonate; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; 5: |Mitsunobu Displacement;
DOI:10.1016/j.bmcl.2013.03.125

Reference yield:

: 861673-68-9
2-(2-(tert-butyl)phenoxy)pyridin-3-amine

: 870552-35-5
C₂₈H₃₃FN₄O₃

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydrogencarbonate / dichloromethane

2: tetrahydrofuran

3: di-tert-butyl-diazodicarboxylate / tetrahydrofuran

4: hydrogen; palladium 10% on activated carbon / methanol

With di-tert-butyl-diazodicarboxylate; palladium 10% on activated carbon; hydrogen; sodium hydrogencarbonate; In tetrahydrofuran; methanol; dichloromethane; 3: |Mitsunobu Displacement;
DOI:10.1016/j.bmcl.2013.03.125