[(1R,2R)-2-Chloro-1-(4-chloro-phenyl)-2-((R)-toluene-4-sulfinyl)-propyl]-phenyl-amine

Base Information

• Chemical Name: [(1R,2R)-2-Chloro-1-(4-chloro-phenyl)-2-((R)-toluene-4-sulfinyl)-propyl]-phenyl-amine
• CAS No.: 122406-42-2
• Molecular Formula: C₂₂H₂₁Cl₂NOS
• Molecular Weight: 418.387

Synonyms:[(1R,2R)-2-Chloro-1-(4-chloro-phenyl)-2-((R)-toluene-4-sulfinyl)-propyl]-phenyl-amine

Chemical Property of [(1R,2R)-2-Chloro-1-(4-chloro-phenyl)-2-((R)-toluene-4-sulfinyl)-propyl]-phenyl-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [(1R,2R)-2-Chloro-1-(4-chloro-phenyl)-2-((R)-toluene-4-sulfinyl)-propyl]-phenyl-amine

There total 3 articles about [(1R,2R)-2-Chloro-1-(4-chloro-phenyl)-2-((R)-toluene-4-sulfinyl)-propyl]-phenyl-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

1-chloroethyl p-tolyl sulfoxide (50635-71-7,50635-72-8,31350-93-3) + N-(4-chlorobenzylidene)aniline (2362-79-0) → [(1S,2S)-2-Chloro-1-(4-chloro-phenyl)-2-(toluene-4-sulfinyl)-propyl]-phenyl-amine (119507-88-9,122406-25-1,122406-42-2)

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; at -60 ℃;

DOI:10.1016/S0040-4039(00)80425-6

Reference yield:

1-chloroethyl p-tolyl sulfoxide (50635-71-7,50635-72-8,31350-93-3) + N-(4-chlorobenzylidene)aniline (2362-79-0) → [(1S,2S)-2-Chloro-1-(4-chloro-phenyl)-2-((S)-toluene-4-sulfinyl)-propyl]-phenyl-amine (119507-88-9,122406-25-1,122406-42-2)

Guidance literature:

With lithium diisopropyl amide; Yield given. Multistep reaction; 1.) THF, -60 deg C, 15 min, 2.) THF, -60 deg C, 5 min;

DOI:10.1021/jo00277a041

Reference yield:

(-)-(R)-1-chloroethyl p-tolyl sulfoxide (31350-93-3,50635-71-7,50635-72-8) + N-(4-chlorobenzylidene)aniline (2362-79-0) → [(1R,2R)-2-Chloro-1-(4-chloro-phenyl)-2-((R)-toluene-4-sulfinyl)-propyl]-phenyl-amine (122406-42-2)

Guidance literature:

With lithium diisopropyl amide; Multistep reaction; 1.) THF, -60 deg C, 15 min, 2.) THF, -60 deg C, 5 min;

DOI:10.1021/jo00277a041

upstream raw materials:

1-chloroethyl p-tolyl sulfoxide

N-(4-chlorobenzylidene)aniline

(-)-(R)-1-chloroethyl p-tolyl sulfoxide

Downstream raw materials:

(Z)-1-phenyl-2-(4-chlorophenyl)-3-methylaziridine

(2R,3R)-3-(4-Chloro-phenyl)-2-methyl-1-phenyl-2-((S)-toluene-4-sulfinyl)-aziridine

(2S,3S)-3-(4-Chloro-phenyl)-2-methyl-1-phenyl-2-((R)-toluene-4-sulfinyl)-aziridine

(2S,3S)-3-(4-Chloro-phenyl)-2-methyl-1-phenyl-2-(toluene-4-sulfinyl)-aziridine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 122406-42-2 [(1R,2R)-2-Chloro-1-(4-chloro-phenyl)-2-((R)-toluene-4-sulfinyl)-propyl]-phenyl-amine

Send

Send

Metric Ton KG G Pound L ML

Send

Send