N₁-(2-azido-7-(2,5-dihydroxyphenyl)heptyl)-N₄-(30-mercapto-7,10,13,16,19-pentaoxatriacontyl)succinamide

Base Information

• Chemical Name: N₁-(2-azido-7-(2,5-dihydroxyphenyl)heptyl)-N₄-(30-mercapto-7,10,13,16,19-pentaoxatriacontyl)succinamide
• CAS No.: 1309932-16-8
• Molecular Formula: C₄₂H₇₅N₅O₉S
• Molecular Weight: 826.152

Synonyms:N₁-(2-azido-7-(2,5-dihydroxyphenyl)heptyl)-N₄-(30-mercapto-7,10,13,16,19-pentaoxatriacontyl)succinamide

Chemical Property of N₁-(2-azido-7-(2,5-dihydroxyphenyl)heptyl)-N₄-(30-mercapto-7,10,13,16,19-pentaoxatriacontyl)succinamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N₁-(2-azido-7-(2,5-dihydroxyphenyl)heptyl)-N₄-(30-mercapto-7,10,13,16,19-pentaoxatriacontyl)succinamide

There total 13 articles about N₁-(2-azido-7-(2,5-dihydroxyphenyl)heptyl)-N₄-(30-mercapto-7,10,13,16,19-pentaoxatriacontyl)succinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

N1-(2-azido-7-(2,5-bis(tetrahydro-2H-pyran-2-yloxy)phenyl)heptyl)-N4-(1,1,1-triphenyl-14,17,20,23,26-pentaoxa-2-thiadotriacontan-32-yl)succinamide (1309932-15-7) → N1-(2-azido-7-(2,5-dihydroxyphenyl)heptyl)-N4-(30-mercapto-7,10,13,16,19-pentaoxatriacontyl)succinamide (1309932-16-8)

Guidance literature:

With triethylsilane; water; trifluoroacetic acid; In dichloromethane; at 25 ℃; for 0.5h;

DOI:10.1021/ja203198y

Reference yield:

7-bromo-hept-1-ene (4117-09-3) → N1-(2-azido-7-(2,5-dihydroxyphenyl)heptyl)-N4-(30-mercapto-7,10,13,16,19-pentaoxatriacontyl)succinamide (1309932-16-8)

Guidance literature:

Multi-step reaction with 9 steps

1.1: tert.-butyl lithium / tetrahydrofuran / 0.75 h / 0 °C

1.2: 3 h

2.1: sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / 3 h / 0 - 25 °C

3.1: sodium hydrogencarbonate / N,N-dimethyl-formamide / 24 h / 90 °C

4.1: triethylamine / tetrahydrofuran / 3 h

5.1: sodium azide / N,N-dimethyl-formamide / 72 h / 110 °C

6.1: hydrazine / methanol / 12 h / 60 °C

7.1: tetrahydrofuran / 0.5 h / 25 °C

8.1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.5 h

8.2: 2 h / 25 °C

9.1: triethylsilane; water; trifluoroacetic acid / dichloromethane / 0.5 h / 25 °C

With triethylsilane; sodium azide; water; tert.-butyl lithium; sodium hydrogencarbonate; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid; trifluoroacetic acid; hydrazine; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/ja203198y

Reference yield:

C23H36N4O4 → N1-(2-azido-7-(2,5-dihydroxyphenyl)heptyl)-N4-(30-mercapto-7,10,13,16,19-pentaoxatriacontyl)succinamide (1309932-16-8)

Guidance literature:

Multi-step reaction with 3 steps

1.1: tetrahydrofuran / 0.5 h / 25 °C

2.1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.5 h

2.2: 2 h / 25 °C

3.1: triethylsilane; water; trifluoroacetic acid / dichloromethane / 0.5 h / 25 °C

With triethylsilane; water; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/ja203198y

upstream raw materials:

1,1,1-triphenyl-14,17,20,23-tetraoxa-2-thiapentacosan-25-ol

1 ,6-dibromohexane

4-(2-azido-7-(2,5-bis(tetrahydro-2H-pyran-2-yloxy)phenyl)heptylamino)-4-oxobutanoic acid

1,1,1-triphenyl-14,17,20,23,26-pentaoxa-2-thiadotriacontan-32-amine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1309932-16-8 N₁-(2-azido-7-(2,5-dihydroxyphenyl)heptyl)-N₄-(30-mercapto-7,10,13,16,19-pentaoxatriacontyl)succinamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send