Technology Process of dibenzyl <2-(2-methyl-1,3-dioxolan-2-yl)-2-oxo-ethyl>-phosphonate
There total 4 articles about dibenzyl <2-(2-methyl-1,3-dioxolan-2-yl)-2-oxo-ethyl>-phosphonate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
pyridine; dicyclohexyl-carbodiimide; trifluoroacetic acid;
In
dimethyl sulfoxide; benzene;
Ambient temperature;
DOI:10.1016/S0968-0896(99)00065-6
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 98 percent / m-CPBA / CH2Cl2 / 120 h / Ambient temperature
2: 1.) n-BuLi, 2.) BF3*OEt2 / 1.) THF, -80 deg C, 30 min, 2.) -70 deg C, 2 h; room temperature, overnight
3: 75 percent / DCC, pyridine, TFA / benzene; dimethylsulfoxide / Ambient temperature
With
pyridine; n-butyllithium; boron trifluoride diethyl etherate; 3-chloro-benzenecarboperoxoic acid; dicyclohexyl-carbodiimide; trifluoroacetic acid;
In
dichloromethane; dimethyl sulfoxide; benzene;
DOI:10.1016/S0968-0896(99)00065-6
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 82 percent / KOH / ethane-1,2-diol / 5 h / 125 °C
2: 98 percent / m-CPBA / CH2Cl2 / 120 h / Ambient temperature
3: 1.) n-BuLi, 2.) BF3*OEt2 / 1.) THF, -80 deg C, 30 min, 2.) -70 deg C, 2 h; room temperature, overnight
4: 75 percent / DCC, pyridine, TFA / benzene; dimethylsulfoxide / Ambient temperature
With
pyridine; potassium hydroxide; n-butyllithium; boron trifluoride diethyl etherate; 3-chloro-benzenecarboperoxoic acid; dicyclohexyl-carbodiimide; trifluoroacetic acid;
In
dichloromethane; ethylene glycol; dimethyl sulfoxide; benzene;
DOI:10.1016/S0968-0896(99)00065-6