1H-Pyrazole-3-carboxylic acid, 4-amino-5-methyl-, 2-(3-chlorophenyl)hydrazide

Base Information

Chemical Name:1H-Pyrazole-3-carboxylic acid, 4-amino-5-methyl-, 2-(3-chlorophenyl)hydrazide
CAS No.:81016-56-0
Molecular Formula:C11H12 Cl N5 O
Molecular Weight:0
Hs Code.:
DSSTox Substance ID:DTXSID70230857
Wikidata:Q83111598
Mol file:81016-56-0.mol

Synonyms:81016-56-0;1H-Pyrazole-3-carboxylic acid, 4-amino-5-methyl-, 2-(3-chlorophenyl)hydrazide;4-Amino-5-methyl-1H-pyrazole-3-carboxylic acid 2-(3-chlorophenyl)hydrazide;C11H12ClN5O;DTXSID70230857;LS-128266;4-AMINO-5-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID 2-(3-CHLOROPHENYL)HYDRA ZIDE

Suppliers and Price of 1H-Pyrazole-3-carboxylic acid, 4-amino-5-methyl-, 2-(3-chlorophenyl)hydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-AMINO-5-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID 2-(3-CHLOROPHENYL)HYDRA ZIDE 95.00%
5MG
$ 499.46

Total 4 raw suppliers

Chemical Property of 1H-Pyrazole-3-carboxylic acid, 4-amino-5-methyl-, 2-(3-chlorophenyl)hydrazide

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:265.0730377
Heavy Atom Count:18
Complexity:303

Purity/Quality:: 4-AMINO-5-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID 2-(3-CHLOROPHENYL)HYDRA ZIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=NN1)C(=O)NNC2=CC(=CC=C2)Cl)N

Technology Process of 1H-Pyrazole-3-carboxylic acid, 4-amino-5-methyl-, 2-(3-chlorophenyl)hydrazide

There total 3 articles about 1H-Pyrazole-3-carboxylic acid, 4-amino-5-methyl-, 2-(3-chlorophenyl)hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 81016-50-4
5-Methyl-4-nitro-2H-pyrazole-3-carboxylic acid N'-(3-chloro-phenyl)-hydrazide

: 81016-56-0
4-Amino-5-methyl-2H-pyrazole-3-carboxylic acid N'-(3-chloro-phenyl)-hydrazide

Guidance literature:: With hydrazine; palladium on activated charcoal; In methanol; for 0.0833333h; Heating;
DOI:10.1055/s-1982-29705

Reference yield:

: 2312-23-4
m-chlorophenylhydrazine hydrochloride

: 81016-56-0
4-Amino-5-methyl-2H-pyrazole-3-carboxylic acid N'-(3-chloro-phenyl)-hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / 1.) KOH / methanol / 1.) 1h; 2.) room temp., overnight

2: 72 percent / hydrazine / 5percent Pd-C / methanol / 0.08 h / Heating

With potassium hydroxide; hydrazine; palladium on activated charcoal; In methanol;
DOI:10.1055/s-1982-29705

Reference yield:

: 80030-73-5
2,7-dimethyl-3,8-dinitrodipyrazolo[1,5-a;1',5'-d]pyrazine-4,9-dione

: 81016-56-0
4-Amino-5-methyl-2H-pyrazole-3-carboxylic acid N'-(3-chloro-phenyl)-hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / 1.) KOH / methanol / 1.) 1h; 2.) room temp., overnight

2: 72 percent / hydrazine / 5percent Pd-C / methanol / 0.08 h / Heating

With potassium hydroxide; hydrazine; palladium on activated charcoal; In methanol;
DOI:10.1055/s-1982-29705