(2R,3S)-5,7-bis(benzyloxy)-2-[3,4-bis(benzyloxy)phenyl]-3,4-dihydro-2H-1-benzopyran-3-yl 3,4-bis(benzyloxy)-5-methoxybenzoate

Base Information

• Chemical Name: (2R,3S)-5,7-bis(benzyloxy)-2-[3,4-bis(benzyloxy)phenyl]-3,4-dihydro-2H-1-benzopyran-3-yl 3,4-bis(benzyloxy)-5-methoxybenzoate
• CAS No.: 1190414-53-9
• Molecular Formula: C₆₅H₅₆O₁₀
• Molecular Weight: 997.154
• Mol file: 1190414-53-9.mol

Synonyms:(2R,3S)-5,7-bis(benzyloxy)-2-[3,4-bis(benzyloxy)phenyl]-3,4-dihydro-2H-1-benzopyran-3-yl 3,4-bis(benzyloxy)-5-methoxybenzoate

Chemical Property of (2R,3S)-5,7-bis(benzyloxy)-2-[3,4-bis(benzyloxy)phenyl]-3,4-dihydro-2H-1-benzopyran-3-yl 3,4-bis(benzyloxy)-5-methoxybenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (2R,3S)-5,7-bis(benzyloxy)-2-[3,4-bis(benzyloxy)phenyl]-3,4-dihydro-2H-1-benzopyran-3-yl 3,4-bis(benzyloxy)-5-methoxybenzoate

There total 1 articles about (2R,3S)-5,7-bis(benzyloxy)-2-[3,4-bis(benzyloxy)phenyl]-3,4-dihydro-2H-1-benzopyran-3-yl 3,4-bis(benzyloxy)-5-methoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

3,4-bis(benzyloxy)-5-methoxybenzoic acid (70845-73-7) + 5,7,3',4'-tetra-O-benzyl-(+)-catechin (20728-73-8) → (2R,3S)-5,7-bis(benzyloxy)-2-[3,4-bis(benzyloxy)phenyl]-3,4-dihydro-2H-1-benzopyran-3-yl 3,4-bis(benzyloxy)-5-methoxybenzoate (1190414-53-9)

Guidance literature:

3,4-bis(benzyloxy)-5-methoxybenzoic acid; With dmap; In dichloromethane; for 0.166667h;

With dicyclohexyl-carbodiimide; In dichloromethane; at 0 ℃; for 0.166667h;

5,7,3',4'-tetra-O-benzyl-(+)-catechin; In dichloromethane; at 0 ℃; for 24h;

DOI:10.1002/cbdv.200800224

Reference yield: 100.0%

(2R,3S)-5,7-bis(benzyloxy)-2-[3,4-bis(benzyloxy)phenyl]-3,4-dihydro-2H-1-benzopyran-3-yl 3,4-bis(benzyloxy)-5-methoxybenzoate (1190414-53-9) → (2R,3S)-3,4-dihydro-5,7-dihydroxy-2-(3,4-dihydroxyphenyl)-2H-1-benzopyran-3-yl 3,4-dihydroxy-5-methoxybenzoate

Guidance literature:

With palladium hydroxide on carbon; hydrogen; In tetrahydrofuran; methanol; water; for 24h;

DOI:10.1002/cbdv.200800224

upstream raw materials:

3,4-bis(benzyloxy)-5-methoxybenzoic acid

5,7,3',4'-tetra-O-benzyl-(+)-catechin