(5S,6R,7R,8S)-6-<8-acetoxy-7,8-dihydro-7-(methoxymethoxy)styryl>-5-(methoxymethoxy)-5,6-dihydro-2H-pyran-2-one

Base Information

Chemical Name:(5S,6R,7R,8S)-6-<8-acetoxy-7,8-dihydro-7-(methoxymethoxy)styryl>-5-(methoxymethoxy)-5,6-dihydro-2H-pyran-2-one
CAS No.:153619-54-6
Molecular Formula:C₁₉H₂₄O₈
Molecular Weight:380.395
Hs Code.:

Synonyms:(5S,6R,7R,8S)-6-<8-acetoxy-7,8-dihydro-7-(methoxymethoxy)styryl>-5-(methoxymethoxy)-5,6-dihydro-2H-pyran-2-one

Suppliers and Price of (5S,6R,7R,8S)-6-<8-acetoxy-7,8-dihydro-7-(methoxymethoxy)styryl>-5-(methoxymethoxy)-5,6-dihydro-2H-pyran-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (5S,6R,7R,8S)-6-<8-acetoxy-7,8-dihydro-7-(methoxymethoxy)styryl>-5-(methoxymethoxy)-5,6-dihydro-2H-pyran-2-one

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (5S,6R,7R,8S)-6-<8-acetoxy-7,8-dihydro-7-(methoxymethoxy)styryl>-5-(methoxymethoxy)-5,6-dihydro-2H-pyran-2-one

There total 11 articles about (5S,6R,7R,8S)-6-<8-acetoxy-7,8-dihydro-7-(methoxymethoxy)styryl>-5-(methoxymethoxy)-5,6-dihydro-2H-pyran-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 108-24-7
acetic anhydride

: 153619-51-3
(5S,6R,7R,8S)-6-<7,8-dihydro-8-hydroxy-7-(methoxymethoxy)styryl>-5-(methoxymethoxy)-5,6-dihydro-2H-pyran-2-one

: 153619-54-6
(5S,6R,7R,8S)-6-<8-acetoxy-7,8-dihydro-7-(methoxymethoxy)styryl>-5-(methoxymethoxy)-5,6-dihydro-2H-pyran-2-one

Guidance literature:: In pyridine; for 3h; Ambient temperature;
DOI:10.1016/S0040-4020(99)00023-X

Reference yield:

: 80541-30-6
(1S,2R)-1-(2-furyl)-2,3-(dimethylmethylen-dioxy)-1-propanol

: 153619-54-6
(5S,6R,7R,8S)-6-<8-acetoxy-7,8-dihydro-7-(methoxymethoxy)styryl>-5-(methoxymethoxy)-5,6-dihydro-2H-pyran-2-one

Guidance literature:: Multi-step reaction with 11 steps

1: 97 percent / NBS, NaOAc / tetrahydrofuran; H₂O / 0.5 h / 0 °C

2: CrO₃ / acetic acid / 0.5 h / Ambient temperature

3: sodium triacetoxyborohydride / propan-2-ol / 0.5 h / -20 °C

4: 83 percent / iPr₂EtN, DMAP / CH₂Cl₂ / 10 h / Ambient temperature

5: 88 percent / AcOH, H₂O / tetrahydrofuran / 8 h / 40 °C

6: 99 percent / Et₃N, DMAP / CH₂Cl₂ / 5 h / Ambient temperature

7: 99 percent / iPr₂EtN, DMAP / CH₂Cl₂ / 10 h / Ambient temperature

8: 98 percent / AcOH, H₂O / tetrahydrofuran / 5 h / 40 °C

9: oxalyl chloride, DMSO / CH₂Cl₂ / 0.5 h

10: 19 percent / Et₃N / 2 h / 0 °C

11: 99 percent / pyridine / 3 h / Ambient temperature

With chromium(VI) oxide; dmap; N-Bromosuccinimide; oxalyl dichloride; water; sodium acetate; sodium tris(acetoxy)borohydride; acetic acid; dimethyl sulfoxide; triethylamine; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; pyridine; dichloromethane; water; acetic acid; isopropyl alcohol;
DOI:10.1016/S0040-4020(99)00023-X

Reference yield:

: 123695-71-6
(2R)-1,2-isopropylidene-3-furyl-3-propanon-1,2-diol

: 153619-54-6
(5S,6R,7R,8S)-6-<8-acetoxy-7,8-dihydro-7-(methoxymethoxy)styryl>-5-(methoxymethoxy)-5,6-dihydro-2H-pyran-2-one

Guidance literature:: Multi-step reaction with 12 steps

1: 84 percent / L-Selectride / tetrahydrofuran / 0.5 h / -78 °C

2: 97 percent / NBS, NaOAc / tetrahydrofuran; H₂O / 0.5 h / 0 °C

3: CrO₃ / acetic acid / 0.5 h / Ambient temperature

4: sodium triacetoxyborohydride / propan-2-ol / 0.5 h / -20 °C

5: 83 percent / iPr₂EtN, DMAP / CH₂Cl₂ / 10 h / Ambient temperature

6: 88 percent / AcOH, H₂O / tetrahydrofuran / 8 h / 40 °C

7: 99 percent / Et₃N, DMAP / CH₂Cl₂ / 5 h / Ambient temperature

8: 99 percent / iPr₂EtN, DMAP / CH₂Cl₂ / 10 h / Ambient temperature

9: 98 percent / AcOH, H₂O / tetrahydrofuran / 5 h / 40 °C

10: oxalyl chloride, DMSO / CH₂Cl₂ / 0.5 h

11: 19 percent / Et₃N / 2 h / 0 °C

12: 99 percent / pyridine / 3 h / Ambient temperature

With chromium(VI) oxide; dmap; N-Bromosuccinimide; oxalyl dichloride; water; sodium acetate; L-Selectride; sodium tris(acetoxy)borohydride; acetic acid; dimethyl sulfoxide; triethylamine; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; pyridine; dichloromethane; water; acetic acid; isopropyl alcohol;
DOI:10.1016/S0040-4020(99)00023-X