N-((2,7-dimethyl-1H-indol-3-yl)(m-tolyl)methyl)-4-methylbenzenesulfonamide

Base Information

Chemical Name:N-((2,7-dimethyl-1H-indol-3-yl)(m-tolyl)methyl)-4-methylbenzenesulfonamide
CAS No.:1357175-07-5
Molecular Formula:C₂₅H₂₆N₂O₂S
Molecular Weight:418.56
Hs Code.:

Synonyms:N-((2,7-dimethyl-1H-indol-3-yl)(m-tolyl)methyl)-4-methylbenzenesulfonamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-((2,7-dimethyl-1H-indol-3-yl)(m-tolyl)methyl)-4-methylbenzenesulfonamide

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Technology Process of N-((2,7-dimethyl-1H-indol-3-yl)(m-tolyl)methyl)-4-methylbenzenesulfonamide

There total 1 articles about N-((2,7-dimethyl-1H-indol-3-yl)(m-tolyl)methyl)-4-methylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 5621-13-6
2,7-dimethyl-1H-indole

: 561319-11-7
4-methyl-N-(3-methylbenzylidene)benzenesulfonamide

: 1357175-07-5
N-((2,7-dimethyl-1H-indol-3-yl)(m-tolyl)methyl)-4-methylbenzenesulfonamide

Guidance literature:: 2,7-dimethyl-1H-indole; With iodine; In dichloromethane; at 0 ℃; for 0.0333333h; Inert atmosphere;

4-methyl-N-(3-methylbenzylidene)benzenesulfonamide; In dichloromethane; at 0 ℃; for 0.05h; Inert atmosphere;
DOI:10.1039/c1ob06777j

Reference yield: 97.0%

: 1357175-07-5
N-((2,7-dimethyl-1H-indol-3-yl)(m-tolyl)methyl)-4-methylbenzenesulfonamide

: 1304141-62-5
(2R,3R)-(-)-2,7-dimethyl-3-(3-methylbenzyl)indoline

Guidance literature:: N-((2,7-dimethyl-1H-indol-3-yl)(m-tolyl)methyl)-4-methylbenzenesulfonamide; With toluene-4-sulfonic acid; In dichloromethane; 2,2,2-trifluoroethanol; at 20 ℃; for 0.0833333h;

With palladium(II) trifluoroacetate; hydrogen; (R)-(+)-2,2'-bis(diphenylphosphanyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl; In dichloromethane; 2,2,2-trifluoroethanol; at 50 ℃; under 31029.7 Torr; optical yield given as %ee; enantioselective reaction; Autoclave;
DOI:10.1039/c1ob06777j