C₂₂H₃₆INO₄

Base Information

• Chemical Name: C₂₂H₃₆INO₄
• CAS No.: 1360873-95-5
• Molecular Formula: C₂₂H₃₆INO₄
• Molecular Weight: 505.437
• Mol file: 1360873-95-5.mol

Synonyms:C₂₂H₃₆INO₄

Chemical Property of C₂₂H₃₆INO₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₃₆INO₄

There total 10 articles about C₂₂H₃₆INO₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

C23H39NO7S → C22H36INO4 (1360873-95-5)

Guidance literature:

With sodium iodide; In acetone; at 20 ℃; for 19h; Inert atmosphere;

DOI:10.1002/anie.201106753

Reference yield:

C28H43NO4Si (1360874-07-2) → C22H36INO4 (1360873-95-5)

Guidance literature:

Multi-step reaction with 6 steps

1: silica gel; pyridinium chlorochromate / dichloromethane / 4 h / 20 °C / Inert atmosphere

2: tetrahydrofuran; diethyl ether / 3 h / -78 °C / Inert atmosphere

3: triethylamine hydrofluoride / acetonitrile / 70 h / 20 °C / Inert atmosphere

4: collidine / dichloromethane / 0 - 20 °C / Inert atmosphere

5: Dess-Martin periodane / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

6: sodium iodide / acetone / 19 h / 20 °C / Inert atmosphere

With silica gel; Dess-Martin periodane; triethylamine hydrofluoride; pyridinium chlorochromate; sodium iodide; In tetrahydrofuran; diethyl ether; dichloromethane; acetone; acetonitrile;

DOI:10.1002/anie.201106753

Reference yield:

(5R)-5-methylcyclohex-2-enone (1360873-92-2) → C22H36INO4 (1360873-95-5)

Guidance literature:

Multi-step reaction with 5 steps

1: tetrahydrofuran; diethyl ether / 3 h / -78 °C / Inert atmosphere

2: triethylamine hydrofluoride / acetonitrile / 70 h / 20 °C / Inert atmosphere

3: collidine / dichloromethane / 0 - 20 °C / Inert atmosphere

4: Dess-Martin periodane / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

5: sodium iodide / acetone / 19 h / 20 °C / Inert atmosphere

With Dess-Martin periodane; triethylamine hydrofluoride; sodium iodide; In tetrahydrofuran; diethyl ether; dichloromethane; acetone; acetonitrile;

DOI:10.1002/anie.201106753

upstream raw materials:

C₂₈H₄₃NO₄Si

(5R)-5-methylcyclohex-2-enone

(R)-5-methyl-cyclohex-2-enone

Downstream raw materials:

(-)-8-deoxyserratinine