5-amino-1,3-dihydro-2,1-benzoxaborol-1-ol

Base Information

Chemical Name:5-amino-1,3-dihydro-2,1-benzoxaborol-1-ol
CAS No.:947165-26-6
Molecular Formula:C₇H₈BNO₂
Molecular Weight:148.957
Hs Code.:

Synonyms:5-amino-1,3-dihydro-2,1-benzoxaborol-1-ol

Suppliers and Price of 5-amino-1,3-dihydro-2,1-benzoxaborol-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-amine
25mg
$ 620.00

Medical Isotopes, Inc.
1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-amine
100 mg
$ 1490.00

Chemenu
1-hydroxy-3H-2,1-benzoxaborol-5-amine 95%+
1g
$ 1250.00

AK Scientific
5-Aminobenzo[c][1,2]oxaborol-1(3H)-ol
1g
$ 1295.00

Total 11 raw suppliers

Chemical Property of 5-amino-1,3-dihydro-2,1-benzoxaborol-1-ol

Chemical Property:

Boiling Point:329.5±52.0 °C(Predicted)
Density:1.27±0.1 g/cm3(Predicted)

Purity/Quality:

99%, ^*data from raw suppliers

1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-amine is a boron compound that can potentially be used for treatment of periodontal disease such as infection involving bacteria, viruses, fungi and/or parasites. 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-amine may also be used as an anti-inflammatory agent.

Technology Process of 5-amino-1,3-dihydro-2,1-benzoxaborol-1-ol

There total 8 articles about 5-amino-1,3-dihydro-2,1-benzoxaborol-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.1%

: 875816-94-7
1,3-dihydro-5-nitro-1-hydroxy-2,1-benzoxaborole

: 947165-26-6
5-amino-1,3-dihydro-2,1-benzoxaborol-1-ol

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; for 1h;

Reference yield:

: 875816-94-7
1,3-dihydro-5-nitro-1-hydroxy-2,1-benzoxaborole

: 1877-77-6
3-aminobenzenemethanol

: 947165-26-6
5-amino-1,3-dihydro-2,1-benzoxaborol-1-ol

Guidance literature:: With hydrogenchloride; zinc; In methanol; at 25 ℃; for 1h; Reagent/catalyst; Solvent;
DOI:10.1002/ejoc.201900013

Reference yield:

: 99-52-5
2-methyl-4-nitro-benzenamine

: 1877-77-6
3-aminobenzenemethanol

: 947165-26-6
5-amino-1,3-dihydro-2,1-benzoxaborol-1-ol

Guidance literature:: Multi-step reaction with 4 steps

1.1: hydrogen bromide; sodium nitrite / water / 0.5 h / 0 °C

1.2: 1 h / 25 °C

2.1: N-Bromosuccinimide; dibenzoyl peroxide / acetonitrile / 24 h / 100 °C / Schlenk technique; Inert atmosphere

3.1: water; 1,4-dioxane / 1 h / 60 °C

3.2: 60 °C

4.1: hydrogenchloride; zinc / methanol / 1 h / 25 °C

With hydrogenchloride; N-Bromosuccinimide; hydrogen bromide; zinc; sodium nitrite; dibenzoyl peroxide; In 1,4-dioxane; methanol; water; acetonitrile;
DOI:10.1002/ejoc.201900013