C₁₈H₁₉NO

Base Information

• Chemical Name: C₁₈H₁₉NO
• CAS No.: 870861-14-6
• Molecular Formula: C₁₈H₁₉NO
• Molecular Weight: 265.355
• Mol file: 870861-14-6.mol

Synonyms:C₁₈H₁₉NO

Chemical Property of C₁₈H₁₉NO

Chemical Property:

Purity/Quality:

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Technology Process of C₁₈H₁₉NO

There total 1 articles about C₁₈H₁₉NO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl (2S)-[allyl(benzyl)amino](phenyl)acetate (870861-34-0) → C18H19NO (870861-14-6)

Guidance literature:

With titanium(IV) isopropylate; isopropylmagnesium bromide; In tetrahydrofuran; diethyl ether; at 20 ℃; for 5h; Inert atmosphere;

DOI:10.1002/ejoc.200800380

Reference yield: 92.0%

C18H19NO (870861-14-6) → (2S)-1-benzyl-2-phenyl-1,6-dihydropyridin-3(2H)-one (1000414-79-8)

Guidance literature:

C₁₈H₁₉NO; With iron(III) chloride; In diethyl ether; at 0 ℃; for 3h; Inert atmosphere;

With sodium acetate; In methanol; diethyl ether; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1002/ejoc.200800380

Reference yield: 40.0%

C18H19NO (870861-14-6) → (2S)-1-benzyl-2-phenyl-1,6-dihydropyridin-3(2H)-one (1000414-79-8) + 1-benzyl-2-phenyl-4-methylpyrrolidin-3-one

Guidance literature:

With bis(2,4,6-trimethylpyridine)iodine(I) hexafluorophosphate; In dichloromethane; at 20 ℃; for 1.5h;

DOI:10.1002/ejoc.200800380

upstream raw materials:

methyl (2S)-[allyl(benzyl)amino](phenyl)acetate

Downstream raw materials:

(2S)-1-benzyl-2-phenyl-1,6-dihydropyridin-3(2H)-one

1-benzyl-2-phenylpiperidin-3-one