cyclopentyl (2S,4E)-2-[(tert-butoxycarbonyl)amino]-5-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]phenyl}pent-4-enoate

Base Information

Chemical Name:cyclopentyl (2S,4E)-2-[(tert-butoxycarbonyl)amino]-5-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]phenyl}pent-4-enoate
CAS No.:1021943-56-5
Molecular Formula:C₄₃H₅₅N₇O₇
Molecular Weight:781.952
Hs Code.:

cyclopentyl (2S,4E)-2-[(tert-butoxycarbonyl)amino]-5-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]phenyl}pent-4-enoate

Synonyms:cyclopentyl (2S,4E)-2-[(tert-butoxycarbonyl)amino]-5-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]phenyl}pent-4-enoate

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Chemical Property of cyclopentyl (2S,4E)-2-[(tert-butoxycarbonyl)amino]-5-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]phenyl}pent-4-enoate

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Technology Process of cyclopentyl (2S,4E)-2-[(tert-butoxycarbonyl)amino]-5-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]phenyl}pent-4-enoate

There total 1 articles about cyclopentyl (2S,4E)-2-[(tert-butoxycarbonyl)amino]-5-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]phenyl}pent-4-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

: 1021943-48-5
cyclopentyl (2S)-2-[(tert-butoxycarbonyl)amino]pent-4-enoate

: 1021943-55-4
4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-N-(4-iodophenyl)-3-methoxybenzamide

: 1021943-56-5
cyclopentyl (2S,4E)-2-[(tert-butoxycarbonyl)amino]-5-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]phenyl}pent-4-enoate

Guidance literature:: With tetrabutylammomium bromide; triethylamine; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In N,N-dimethyl-formamide; at 120 ℃; for 1h; Microwave irradiation;

Reference yield: 100.0%

: 1021943-56-5
cyclopentyl (2S,4E)-2-[(tert-butoxycarbonyl)amino]-5-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]phenyl}pent-4-enoate

: 1021943-57-6
C₄₃H₅₇N₇O₇

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; at 25 ℃; for 0.5h; under 750.075 Torr;

Reference yield: 75.0%

: 1021943-56-5
cyclopentyl (2S,4E)-2-[(tert-butoxycarbonyl)amino]-5-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]phenyl}pent-4-enoate

: 1021943-58-7
cyclopentyl N-(tert-butoxycarbonyl)-5-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]phenyl}-4-hydroxy-L-norvalinate

Guidance literature:: cyclopentyl (2S,4E)-2-[(tert-butoxycarbonyl)amino]-5-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]phenyl}pent-4-enoate; With dimethylsulfide borane complex; In tetrahydrofuran; at 0 ℃; for 5h;

With sodium perborate; ethanol; water; In tetrahydrofuran; at 0 - 20 ℃; for 11h;