Technology Process of C57H66N8O11
There total 10 articles about C57H66N8O11 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C32H36N4O7;
With
HATU;
In
tetrahydrofuran;
at 0 ℃;
for 0.166667h;
Inert atmosphere;
With
N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran;
at 20 ℃;
for 8h;
Inert atmosphere;
C25H32N4O5*ClH;
In
tetrahydrofuran;
at 20 ℃;
Inert atmosphere;
DOI:10.1016/j.tet.2011.06.032
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: HATU / dichloromethane / 0.33 h / 0 °C / Inert atmosphere
1.2: 36 h / 20 °C / Inert atmosphere
2.1: hydrogenchloride; palladium 10% on activated carbon; hydrogen / methanol; isopropyl alcohol / 8 h / 20 °C / 760.05 Torr
3.1: HATU / tetrahydrofuran / 0.17 h / 0 °C / Inert atmosphere
3.2: 6 h / 20 °C / Inert atmosphere
3.3: 18 h / 20 °C / Inert atmosphere
4.1: hydrogenchloride; palladium 10% on activated carbon; hydrogen / methanol; isopropyl alcohol / 20 °C / 760.05 Torr
5.1: HATU / tetrahydrofuran / 0.17 h / 0 °C / Inert atmosphere
5.2: 8 h / 20 °C / Inert atmosphere
5.3: 20 °C / Inert atmosphere
With
hydrogenchloride; palladium 10% on activated carbon; hydrogen; HATU;
In
tetrahydrofuran; methanol; dichloromethane; isopropyl alcohol;
DOI:10.1016/j.tet.2011.06.032
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: hydrogenchloride; palladium 10% on activated carbon; hydrogen / methanol; isopropyl alcohol / 8 h / 20 °C / 760.05 Torr
2.1: HATU / tetrahydrofuran / 0.17 h / 0 °C / Inert atmosphere
2.2: 6 h / 20 °C / Inert atmosphere
2.3: 18 h / 20 °C / Inert atmosphere
3.1: hydrogenchloride; palladium 10% on activated carbon; hydrogen / methanol; isopropyl alcohol / 20 °C / 760.05 Torr
4.1: HATU / tetrahydrofuran / 0.17 h / 0 °C / Inert atmosphere
4.2: 8 h / 20 °C / Inert atmosphere
4.3: 20 °C / Inert atmosphere
With
hydrogenchloride; palladium 10% on activated carbon; hydrogen; HATU;
In
tetrahydrofuran; methanol; isopropyl alcohol;
DOI:10.1016/j.tet.2011.06.032