1,8-Naphthyridine-3-carboxamide, 1,2-dihydro-4-hydroxy-2-oxo-1-phenyl- N-4-pyridinyl-, hydrate (5:3)

Base Information

Chemical Name:1,8-Naphthyridine-3-carboxamide, 1,2-dihydro-4-hydroxy-2-oxo-1-phenyl- N-4-pyridinyl-, hydrate (5:3)
CAS No.:138304-91-3
Molecular Formula:C₂₀H₁₄N₄O₃
Molecular Weight:358.356
Hs Code.:
Mol file:138304-91-3.mol

Synonyms:1,8-Naphthyridine-3-carboxamide, 1,2-dihydro-4-hydroxy-2-oxo-1-phenyl- N-4-pyridinyl-, hydrate (5:3)

Suppliers and Price of 1,8-Naphthyridine-3-carboxamide, 1,2-dihydro-4-hydroxy-2-oxo-1-phenyl- N-4-pyridinyl-, hydrate (5:3)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1,8-NAPHTHYRIDINE-3-CARBOXAMIDE, 1,2-DIHYDRO-4-HYDROXY-2-OXO-1-PHENYL-N-4-PYRIDINYL-, HYDRATE (5:3) 95.00%
5MG
$ 498.00

Total 1 raw suppliers

Chemical Property of 1,8-Naphthyridine-3-carboxamide, 1,2-dihydro-4-hydroxy-2-oxo-1-phenyl- N-4-pyridinyl-, hydrate (5:3)

Chemical Property:

Vapor Pressure:7.55E-15mmHg at 25°C
Boiling Point:591.7°Cat760mmHg
Flash Point:311.7°C
PSA：100.34000
Density:1.497g/cm³
LogP:2.16050

Purity/Quality:: 1,8-NAPHTHYRIDINE-3-CARBOXAMIDE, 1,2-DIHYDRO-4-HYDROXY-2-OXO-1-PHENYL-N-4-PYRIDINYL-, HYDRATE (5:3) 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1,8-Naphthyridine-3-carboxamide, 1,2-dihydro-4-hydroxy-2-oxo-1-phenyl- N-4-pyridinyl-, hydrate (5:3)

There total 3 articles about 1,8-Naphthyridine-3-carboxamide, 1,2-dihydro-4-hydroxy-2-oxo-1-phenyl- N-4-pyridinyl-, hydrate (5:3) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 504-24-5
4-aminopyridine

: 138305-20-1
1-phenyl-4-hydroxy-pyrido[2,3-b]pyridine-2(1H)-one-3-carboxylic acid ethyl ester

: 138304-91-3
4-Hydroxy-2-oxo-1-phenyl-N-(pyridin-4-yl)-1H-1,8-naphthyridine-3-carboxamide

Guidance literature:: In xylene; for 2h; Heating;
DOI:10.1021/jm00084a019

Reference yield: 51.0%

: 138304-91-3
4-Hydroxy-2-oxo-1-phenyl-N-(pyridin-4-yl)-1H-1,8-naphthyridine-3-carboxamide

Guidance literature:

Reference yield:

: 138305-19-8
1-phenyl-2H-pyrido<2,3-d><1,3>oxazine-2,4(1H)-dione

: 138304-91-3
4-Hydroxy-2-oxo-1-phenyl-N-(pyridin-4-yl)-1H-1,8-naphthyridine-3-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) dimethylacetamide, 2.) dimethylacetamide, 150 deg C, 2.5 h

2: 51 percent / xylene / 2 h / Heating

With sodium hydride; In xylene;
DOI:10.1021/jm00084a019