ethyl 2-((4-methoxyphenyl)amino)-3-methylhept-3-enoate

Base Information

• Chemical Name: ethyl 2-((4-methoxyphenyl)amino)-3-methylhept-3-enoate
• CAS No.: 1427300-01-3
• Molecular Formula: C₁₇H₂₅NO₃
• Molecular Weight: 291.39
• Mol file: 1427300-01-3.mol

Synonyms:ethyl 2-((4-methoxyphenyl)amino)-3-methylhept-3-enoate

Chemical Property of ethyl 2-((4-methoxyphenyl)amino)-3-methylhept-3-enoate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of ethyl 2-((4-methoxyphenyl)amino)-3-methylhept-3-enoate

There total 2 articles about ethyl 2-((4-methoxyphenyl)amino)-3-methylhept-3-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

hexa-1,3-diene (592-48-3) + ethyl (4-methoxyphenylimino)acetate (124156-21-4) → ethyl 2-((4-methoxyphenyl)amino)-3-methylhept-3-enoate (1427300-01-3)

Guidance literature:

With (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II); isopropyl alcohol; In toluene; at 130 ℃; for 24h; regioselective reaction; Inert atmosphere; Sealed tube;

DOI:10.1021/ol4006079

Reference yield:

N-methyl-N-(4-methoxyphenyl)amine (5961-59-1) → ethyl 2-((4-methoxyphenyl)amino)-3-methylhept-3-enoate (1427300-01-3)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium sulfate / toluene / 0.5 h / 20 °C / Inert atmosphere

2: (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II); isopropyl alcohol / toluene / 24 h / 130 °C / Inert atmosphere; Sealed tube

With (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II); sodium sulfate; isopropyl alcohol; In toluene;

DOI:10.1021/ol4006079

upstream raw materials:

hexa-1,3-diene

ethyl (4-methoxyphenylimino)acetate

N-methyl-N-(4-methoxyphenyl)amine

Refernces