1-deoxy-1-(6-{4-[(pyridin-4-ylcarbamoyl)methoxy]phenylamino}-9H-purin-9-yl)-N-ethyl-2,3-O-(1-methylethylidene)-β-D-ribofuranuronamide

Base Information

Chemical Name:1-deoxy-1-(6-{4-[(pyridin-4-ylcarbamoyl)methoxy]phenylamino}-9H-purin-9-yl)-N-ethyl-2,3-O-(1-methylethylidene)-β-D-ribofuranuronamide
CAS No.:936632-78-9
Molecular Formula:C₂₈H₃₀N₈O₆
Molecular Weight:574.596
Hs Code.:

Synonyms:1-deoxy-1-(6-{4-[(pyridin-4-ylcarbamoyl)methoxy]phenylamino}-9H-purin-9-yl)-N-ethyl-2,3-O-(1-methylethylidene)-β-D-ribofuranuronamide

Suppliers and Price of 1-deoxy-1-(6-{4-[(pyridin-4-ylcarbamoyl)methoxy]phenylamino}-9H-purin-9-yl)-N-ethyl-2,3-O-(1-methylethylidene)-β-D-ribofuranuronamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-deoxy-1-(6-{4-[(pyridin-4-ylcarbamoyl)methoxy]phenylamino}-9H-purin-9-yl)-N-ethyl-2,3-O-(1-methylethylidene)-β-D-ribofuranuronamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-deoxy-1-(6-{4-[(pyridin-4-ylcarbamoyl)methoxy]phenylamino}-9H-purin-9-yl)-N-ethyl-2,3-O-(1-methylethylidene)-β-D-ribofuranuronamide

There total 4 articles about 1-deoxy-1-(6-{4-[(pyridin-4-ylcarbamoyl)methoxy]phenylamino}-9H-purin-9-yl)-N-ethyl-2,3-O-(1-methylethylidene)-β-D-ribofuranuronamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 936633-18-0
2-(4-aminophenoxy)-N-pyridin-4-ylacetamide

: 924281-79-8
1-deoxy-1-(6-iodo-9H-purin-9-yl)-2,3-O-isopropylidene-N-ethyl-β-D-ribofuranuronamide

: 936632-78-9
1-deoxy-1-(6-{4-[(pyridin-4-ylcarbamoyl)methoxy]phenylamino}-9H-purin-9-yl)-N-ethyl-2,3-O-(1-methylethylidene)-β-D-ribofuranuronamide

Guidance literature:: With triethylamine; In ethanol; at 100 - 110 ℃; for 12h;
DOI:10.1016/j.bmc.2007.01.055

Reference yield:

: 504-24-5
4-aminopyridine

: 936632-78-9
1-deoxy-1-(6-{4-[(pyridin-4-ylcarbamoyl)methoxy]phenylamino}-9H-purin-9-yl)-N-ethyl-2,3-O-(1-methylethylidene)-β-D-ribofuranuronamide

Guidance literature:: Multi-step reaction with 4 steps

1: 58 percent / K₂CO₃ / CH₂Cl₂ / 4 h / Heating

2: 65 percent / K₂CO₃ / acetone / 12 h / Heating

3: 45 percent / NaBH₄ / Pd/C / methanol; H₂O / 20 °C

4: 35 percent / triethylamine / ethanol / 12 h / 100 - 110 °C

With sodium tetrahydroborate; potassium carbonate; triethylamine; palladium on activated charcoal; In methanol; ethanol; dichloromethane; water; acetone;
DOI:10.1016/j.bmc.2007.01.055

Reference yield:

: 303225-67-4
2-(4-nitrophenoxy)-N-pyridin-4-ylacetamide

: 936632-78-9
1-deoxy-1-(6-{4-[(pyridin-4-ylcarbamoyl)methoxy]phenylamino}-9H-purin-9-yl)-N-ethyl-2,3-O-(1-methylethylidene)-β-D-ribofuranuronamide

Guidance literature:: Multi-step reaction with 2 steps

1: 45 percent / NaBH₄ / Pd/C / methanol; H₂O / 20 °C

2: 35 percent / triethylamine / ethanol / 12 h / 100 - 110 °C

With sodium tetrahydroborate; triethylamine; palladium on activated charcoal; In methanol; ethanol; water;
DOI:10.1016/j.bmc.2007.01.055