13-[(4-tert-butylpiperazin-1-yl)carbonyl]-4-[1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-9-oxa-3,6-diazatricyclo[8.4.0.0^2,6]tetradeca1⁽¹⁴⁾,2,4,10,12-pentaene

Base Information

• Chemical Name: 13-[(4-tert-butylpiperazin-1-yl)carbonyl]-4-[1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-9-oxa-3,6-diazatricyclo[8.4.0.0^2,6]tetradeca1⁽¹⁴⁾,2,4,10,12-pentaene
• CAS No.: 1401302-51-9
• Molecular Formula: C₂₅H₃₃N₇O₂
• Molecular Weight: 463.583

Synonyms:13-[(4-tert-butylpiperazin-1-yl)carbonyl]-4-[1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-9-oxa-3,6-diazatricyclo[8.4.0.0^2,6]tetradeca1⁽¹⁴⁾,2,4,10,12-pentaene

Chemical Property of 13-[(4-tert-butylpiperazin-1-yl)carbonyl]-4-[1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-9-oxa-3,6-diazatricyclo[8.4.0.0^2,6]tetradeca1⁽¹⁴⁾,2,4,10,12-pentaene

Chemical Property:

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Technology Process of 13-[(4-tert-butylpiperazin-1-yl)carbonyl]-4-[1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-9-oxa-3,6-diazatricyclo[8.4.0.0^2,6]tetradeca1⁽¹⁴⁾,2,4,10,12-pentaene

There total 1 articles about 13-[(4-tert-butylpiperazin-1-yl)carbonyl]-4-[1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-9-oxa-3,6-diazatricyclo[8.4.0.0^2,6]tetradeca1⁽¹⁴⁾,2,4,10,12-pentaene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

4-[1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-9-oxa-3,6-diazatricyclo[8.4.0.02,6]tetradeca-1(14),2,4,10,12-pentaene-13-carboxylic acid (1282518-64-2) + 1-(1,1-dimethylethyl)-piperazine (38216-72-7) → 13-[(4-tert-butylpiperazin-1-yl)carbonyl]-4-[1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-9-oxa-3,6-diazatricyclo[8.4.0.02,6]tetradeca1(14),2,4,10,12-pentaene (1401302-51-9)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 100 ℃; for 2h;

upstream raw materials:

4-[1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-9-oxa-3,6-diazatricyclo[8.4.0.0^2,6]tetradeca-1⁽¹⁴⁾,2,4,10,12-pentaene-13-carboxylic acid

1-(1,1-dimethylethyl)-piperazine

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