5-AMino-3-cyano-4-iodo-1-[2,6-dichloro-4-(trifluoroMethyl)phenyl]pyrazole

Base Information

Chemical Name:5-AMino-3-cyano-4-iodo-1-[2,6-dichloro-4-(trifluoroMethyl)phenyl]pyrazole
CAS No.:188539-59-5
Molecular Formula:C₁₁H₄Cl₂F₃IN₄
Molecular Weight:446.985
Hs Code.:
Mol file:188539-59-5.mol

Synonyms:5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-iodo-1H-pyrazole-3-carbonitrile

Suppliers and Price of 5-AMino-3-cyano-4-iodo-1-[2,6-dichloro-4-(trifluoroMethyl)phenyl]pyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Amino-3-cyano-4-iodo-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]pyrazole
100mg
$ 820.00

Medical Isotopes, Inc.
5-Amino-3-cyano-4-iodo-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]pyrazole
25 mg
$ 750.00

Total 2 raw suppliers

Chemical Property of 5-AMino-3-cyano-4-iodo-1-[2,6-dichloro-4-(trifluoroMethyl)phenyl]pyrazole

Chemical Property:

Melting Point:218-220 °C(Solv: acetone (67-64-1); ethanol (64-17-5))
Boiling Point:482.2±45.0 °C(Predicted)
PKA:-3.29±0.14(Predicted)
Density:2.10±0.1 g/cm3(Predicted)
Storage Temp.:Refrigerator
Solubility.:Chloroform, DMSO, Ethyl Acetate, Methanol

Purity/Quality:

99%+ ^*data from raw suppliers

5-Amino-3-cyano-4-iodo-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]pyrazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 5-Amino-3-cyano-4-iodo-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]pyrazole is an intermediate in the synthesis of Fipronil (F342200), an broad spectrum insecticide which actively disrupts the CNS of contacted insects by blocking the passage of chloride ions through GABA receptors.

Technology Process of 5-AMino-3-cyano-4-iodo-1-[2,6-dichloro-4-(trifluoroMethyl)phenyl]pyrazole

There total 4 articles about 5-AMino-3-cyano-4-iodo-1-[2,6-dichloro-4-(trifluoroMethyl)phenyl]pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 120068-79-3
5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole

: 188539-59-5
5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-iodo-1H-pyrazole-3-carbonitrile

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; N-iodo-succinimide; copper(l) iodide; caesium carbonate; In dimethyl sulfoxide; at 100 ℃; for 18h; Solvent; Schlenk technique;
DOI:10.1002/jhet.2628