(αE)-α-[[1-acetyl-5-(phenylmethoxy)-1H-indol-3-yl]methylene]-2-methoxybenzeneacetic acid

Base Information

Chemical Name:(αE)-α-[[1-acetyl-5-(phenylmethoxy)-1H-indol-3-yl]methylene]-2-methoxybenzeneacetic acid
CAS No.:1450604-57-5
Molecular Formula:C₂₇H₂₃NO₅
Molecular Weight:441.483
Hs Code.:

Synonyms:(αE)-α-[[1-acetyl-5-(phenylmethoxy)-1H-indol-3-yl]methylene]-2-methoxybenzeneacetic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (αE)-α-[[1-acetyl-5-(phenylmethoxy)-1H-indol-3-yl]methylene]-2-methoxybenzeneacetic acid

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Technology Process of (αE)-α-[[1-acetyl-5-(phenylmethoxy)-1H-indol-3-yl]methylene]-2-methoxybenzeneacetic acid

There total 1 articles about (αE)-α-[[1-acetyl-5-(phenylmethoxy)-1H-indol-3-yl]methylene]-2-methoxybenzeneacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 93-25-4
2-methoxyphenylacetic acid

: 6953-22-6
5-benzyloxyindole-3-carboxaldehyde

: 1450604-57-5
(αE)-α-[[1-acetyl-5-(phenylmethoxy)-1H-indol-3-yl]methylene]-2-methoxybenzeneacetic acid

Guidance literature:: 2-methoxyphenylacetic acid; 5-benzyloxyindole-3-carboxaldehyde; With acetic anhydride; triethylamine; at 130 ℃; for 6h;

With water; In tetrahydrofuran; ethanol; at 22 - 90 ℃; for 16h;
DOI:10.1016/j.bmc.2013.06.030