Technology Process of 2-[2-tert-butylsulfinyl-3-methoxyphenyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane
There total 2 articles about 2-[2-tert-butylsulfinyl-3-methoxyphenyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
1-(tert-butylsulfinyl)-2-methoxybenzene;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 2h;
Inert atmosphere;
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 16h;
DOI:10.1039/b716954j
- Guidance literature:
-
With
Li(CH2)3CH3;
In
tetrahydrofuran;
(under Ar, Schlenk); B-compound added to soln. of ligand in THF at -78°C, stirred for 16 h; quenched with sat. NH4Cl soln., sepd., aq. layer extd. with ethyl acetate, washed with brine, dried over MgSO4, filtered, concd. under reduced pressure, flash column chromy. with EtOAc-MeOH (95:5);
DOI:10.1039/b716954j
