N-(4-methoxyphenyl)-4-nitrobenzylamine oxime

Base Information

• Chemical Name: N-(4-methoxyphenyl)-4-nitrobenzylamine oxime
• CAS No.: 96633-78-2
• Molecular Formula: C₁₄H₁₃N₃O₄
• Molecular Weight: 287.275
• Mol file: 96633-78-2.mol

Synonyms:N-(4-methoxyphenyl)-4-nitrobenzylamine oxime

Chemical Property of N-(4-methoxyphenyl)-4-nitrobenzylamine oxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-methoxyphenyl)-4-nitrobenzylamine oxime

There total 2 articles about N-(4-methoxyphenyl)-4-nitrobenzylamine oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-nitrobenzaldehyde oxime (1129-37-9,174848-02-3,20707-69-1) → N-(4-methoxyphenyl)-4-nitrobenzylamine oxime (96633-78-2)

Guidance literature:

Multi-step reaction with 2 steps

1: N-chloro-succinimide / N,N-dimethyl-formamide / 0 °C

2: N,N-dimethyl-formamide / 0 - 20 °C

With N-chloro-succinimide; In N,N-dimethyl-formamide;

DOI:10.1016/j.tet.2016.03.070

Reference yield:

4-nitrobenzaldehdye (555-16-8) → N-(4-methoxyphenyl)-4-nitrobenzylamine oxime (96633-78-2)

Guidance literature:

Multi-step reaction with 3 steps

1: hydroxylamine hydrochloride / ethanol / 0 °C

2: N-chloro-succinimide / N,N-dimethyl-formamide / 0 °C

3: N,N-dimethyl-formamide / 0 - 20 °C

With N-chloro-succinimide; hydroxylamine hydrochloride; In ethanol; N,N-dimethyl-formamide;

DOI:10.1016/j.tet.2016.03.070

Reference yield: 75.0%

N-(4-methoxyphenyl)-4-nitrobenzylamine oxime (96633-78-2) → 5-methoxy-2-(4’-nitrophenyl)-1H-benzimidazole (190439-39-5)

Guidance literature:

With p-toluenesulfonylanhydride; triethylamine; In tetrahydrofuran; at -20 - 20 ℃; for 4h; Inert atmosphere;

DOI:10.1002/jccs.201700104

upstream raw materials:

4-nitrobenzaldehyde oxime

4-nitrobenzaldehdye

Downstream raw materials:

3-(4-methoxy-phenyl)-4-(4-nitro-phenyl)-2-(4-nitro-phenylimino)-2,3-dihydro-2λ⁴-[1,2,3,5]oxathiadiazole

5-methoxy-2-(4’-nitrophenyl)-1H-benzimidazole