18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin, 4-(bromomethyl)-10-<3-(bromomethyl)-2-ethoxyphenyl>-19-ethoxy-7,8-dihydro-

Base Information

• Chemical Name: 18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin, 4-(bromomethyl)-10-<3-(bromomethyl)-2-ethoxyphenyl>-19-ethoxy-7,8-dihydro-
• CAS No.: 123291-92-9
• Molecular Formula: C₃₃H₃₂Br₂O₄
• Molecular Weight: 652.423
• Mol file: 123291-92-9.mol

Synonyms:18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin, 4-(bromomethyl)-10-<3-(bromomethyl)-2-ethoxyphenyl>-19-ethoxy-7,8-dihydro-

Chemical Property of 18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin, 4-(bromomethyl)-10-<3-(bromomethyl)-2-ethoxyphenyl>-19-ethoxy-7,8-dihydro-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin, 4-(bromomethyl)-10-<3-(bromomethyl)-2-ethoxyphenyl>-19-ethoxy-7,8-dihydro-

There total 2 articles about 18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin, 4-(bromomethyl)-10-<3-(bromomethyl)-2-ethoxyphenyl>-19-ethoxy-7,8-dihydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin-4-methanol, 19-ethoxy-10-<2-ethoxy-3-(hydroxymethyl)phenyl>-7,8-dihydro- (123291-91-8) → 18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin, 4-(bromomethyl)-10-<3-(bromomethyl)-2-ethoxyphenyl>-19-ethoxy-7,8-dihydro- (123291-92-9)

Guidance literature:

With phosphorus tribromide; In benzene; at 25 ℃; for 1h;

DOI:10.1021/jo00284a018

Reference yield:

18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin-4-carboxylic acid, 19-ethoxy-10-<2-ethoxy-3-(ethoxycarbonyl)phenyl>-7,8-dihydro-, ethyl ester (123291-90-7) → 18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin, 4-(bromomethyl)-10-<3-(bromomethyl)-2-ethoxyphenyl>-19-ethoxy-7,8-dihydro- (123291-92-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 69 percent / LiAlH₄ / diethyl ether / 18 h

2: 68 percent / PBr₃ / benzene / 1 h / 25 °C

With lithium aluminium tetrahydride; phosphorus tribromide; In diethyl ether; benzene;

DOI:10.1021/jo00284a018

upstream raw materials:

18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin-4-methanol, 19-ethoxy-10-<2-ethoxy-3-(hydroxymethyl)phenyl>-7,8-dihydro-

18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin-4-carboxylic acid, 19-ethoxy-10-<2-ethoxy-3-(ethoxycarbonyl)phenyl>-7,8-dihydro-, ethyl ester