benzyl methyl diazomalonate

Base Information

• Chemical Name: benzyl methyl diazomalonate
• CAS No.: 32786-22-4
• Molecular Formula: C₁₁H₁₀N₂O₄
• Molecular Weight: 234.211
• Mol file: 32786-22-4.mol

Synonyms:benzyl methyl diazomalonate

Chemical Property of benzyl methyl diazomalonate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of benzyl methyl diazomalonate

There total 2 articles about benzyl methyl diazomalonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl methyl malonate (52267-39-7) → benzyl methyl diazomalonate (32786-22-4)

Guidance literature:

With 4-toluenesulfonyl azide; triethylamine; In benzene; for 15h; Ambient temperature;

DOI:10.1080/00397919608003756

Reference yield:

→ benzyl methyl diazomalonate (32786-22-4)

Guidance literature:

Verb.1a, TsN3;

DOI:10.1016/S0040-4020(01)93524-0

Reference yield: 87.0%

8-methylquinoline (611-32-5) + benzyl methyl diazomalonate (32786-22-4) → (RS)-1-benzyl 3-methyl 2-(quinolin-8-ylmethyl)malonate

Guidance literature:

With silver hexafluoroantimonate; carbonyl(pentamethylcyclopentadienyl)cobalt diiodide; manganese(II) acetate; In dichloromethane; at 120 ℃; for 12h; Inert atmosphere;

DOI:10.1002/adsc.201700636

upstream raw materials:

benzyl methyl malonate

Refernces

• 1、 Yu, Yunliang,Kuai, Changsheng,Chauvin, Remi,Tian, Nian,Ma, Shuangshuang,Cui, Xiuling. "Rh-Catalyzed Regioselective ortho-C-H Carbenoid Insertion of Diarylazines". . p. 8611 - 8616. Retrieved 2017/08/23.